Eccentric and antisocial detective who shares an apartment with Watson. Possesses exceptional forensic and deductive skills, initially suspected by Watson of being a criminal mastermind before proving himself a world-class investigator. Solves the mysterious death of Helen Stoner's sister and the murders of Enoch Drebber and Joseph Stangerson.
Stamford acts as Holmes's social connection to the returning military doctor.
Stamford is explicitly described as Sherlock Holmes's friend and recommends the vacancy at 221B Baker Street.
Holmes investigates the danger surrounding Helen and the death of Julia.
Helen Stoner visits Holmes as a fearful client and asks for help because she believes her stepfather threatens her.
Holmes opposes Roylott's lethal scheme against Helen.
Holmes investigates Roylott's threatening conduct, examines the bedroom and ventilation shaft, and enters Roylott's room during the snake incident.
Holmes's unconventional deductions compete with Lestrade's police investigation.
Holmes clashes with Inspector Lestrade over the direction of the Drebber investigation.
Gregson brings Holmes into the second murder investigation.
Inspector Gregson invites Holmes to investigate Enoch Drebber's death and later discusses the case with him.
Holmes identifies and exposes the murderer.
Holmes recognizes Hope from Drebber's correspondence and arrests him when he appears as the cab driver called to the scene.
Related entry on Wikidata (Q4653), public domain (CC0).