World-class detective residing at 221B Baker Street. Known for exceptional forensic and deductive skills, alongside eccentric and antisocial traits. Solves the mysterious snake-related death of Julia Stoner and the double murder of Drebber and Stangerson. Arrests Jefferson Hope and laments that a detective's duty is to find the truth, regardless of moral sympathy.
Stangerson's death supplies decisive forensic evidence for Holmes's investigation.
Holmes examines Stangerson's hotel-room murder and interprets the two pills to establish the poisoning method.
Drebber's murder becomes the central case through which Holmes exposes the killer.
Holmes examines Drebber's body, finds a gold ring, deduces poisoning, and traces correspondence that helps identify Hope.
Holmes uncovers Hope's identity and brings the avenger into custody.
Holmes deduces the cabby's identity and arrests Jefferson Hope as the murderer; Hope then confirms Holmes's reconstruction of the crimes.
Gregson relies on Holmes's expertise while remaining part of the official investigation.
Gregson invites Holmes to investigate Enoch Drebber's death, and Holmes later discusses the case with Gregson and Lestrade.
Holmes's deductive approach conflicts with Lestrade's conventional police investigation.
Holmes clashes with Lestrade over the direction of the Drebber investigation, although both continue examining the murders.
Related entry on Wikidata (Q4653), public domain (CC0).