Protagonist who forgets his anniversary with Minnie. To afford a trip to Hawaii, he accepts a job offer from a mad scientist, undergoing a brain-transplant experiment that accidentally swaps his mind into a monstrous body. He must rescue Minnie from the brain-swapped monster, eventually regaining his own body after an electrocution and defeating his foe to reunite with Minnie.
Mickey and Minnie are a romantic couple navigating a forgotten anniversary crisis.
Julius becomes the primary antagonist after the brain swap, directly opposing Mickey.
Pluto acts as a loyal companion who assists Mickey during his financial panic.
Explore the full interactive character relationship map of Runaway Brain