The seemingly deceased criminal mastermind whose body falls into a sewer after a confrontation with Holmes. Actually alive, he is behind a plot to organize drug dealing and the murder of rival crime lords. He also manipulated Holmes' brother Mycroft into opium addiction during their youth.
Watson actively investigates the criminal network orchestrated by the supposedly dead mastermind.
Moriarty exerted psychological and physical control over Mycroft through forced addiction.
Lestrade's official skepticism creates friction with the investigation targeting Moriarty's operations.
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