An Amazonian shaman in 1909 who prolongs the life of the sick German ethnographer Theo using a hallucinogenic powder. Reluctant to involve himself with Westerners and refuses payment, he joins Theo's canoe journey to search for the sacred yakruna plant. Later, he becomes furious upon discovering the plant being abused and cultivated against tradition at a frontier post, leading him to destroy it.
Manduca acts as a bridge between the westerners and the shaman during the expedition.
A tense dynamic where Karamakate aids Theo only out of necessity despite cultural distrust.
Evan gains Karamakate's trust through shared botanical passion and respect for the past.
Karamakate earns the mission leader's admiration through traditional healing practices.
The shaman's resistance to colonial religious oppression puts him at odds with the mission.
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