Lilo (played by Daveigh Chase) is a protagonist in Lilo & Stitch.
Orphaned Hawaiian girl who adopts an alien experiment, teaching him about family and love. Stitch (played by Chris Sanders) is a protagonist in Lilo & Stitch.
Genetically engineered alien experiment 626, initially destructive but learns loyalty and ʻohana. Nani (played by Tia Carrere) appears in Lilo & Stitch.
Lilo's older sister struggling to maintain custody while working multiple jobs. Jumba (played by David Ogden Stiers) appears in Lilo & Stitch.
Mad scientist who illegally created Stitch, later becomes a reluctant protector. Pleakley (played by Kevin McDonald) appears in Lilo & Stitch.
Alien expert on Earth culture who assists Jumba, known for his anxious personality. Grand Councilwoman (played by Zoe Caldwell) appears in Lilo & Stitch.
Leader of the Galactic Federation who oversees the capture of rogue experiments. Cobra Bubbles (played by Ving Rhames) appears in Lilo & Stitch.
Former CIA agent turned social worker, stern but ultimately protects Lilo and Nani. Captain Gantu (played by Kevin Michael Richardson) appears in Lilo & Stitch.
Physically imposing alien captain pursuing Stitch, later becomes a recurring antagonist.
