Rebecca Adler (Robin Tunney), a 29-year-old kindergarten teacher, becomes aphasic and collapses from a seizure in her classroom. Dr. Gregory House initially refuses the case until Dr. James Wilson tells him that Rebecca is his cousin. When Dr. Lisa Cuddy tries to make House fulfill his clinical duties, he refuses but is forced to do them when his authorization to the MRI is revoked. He diagnoses Rebecca with cerebral vasculitis and her condition improves with treatment. To find the source of Reb
A 16-year-old high school student, Dan (Scott Mechlowicz), starts suffering night terrors and frequent hallucinations after playing lacrosse at school. Dan's parents take him to see Dr. House after receiving a letter that Cameron sent in House's name. Upon meeting the family, House begins a bet to determine whether they are his biological parents. After Dan exhibits more symptoms, including a myoclonic twitch and a blocked blood vessel, House diagnoses Dan. Dan suffers from an auditory hallucina
A college student named Brandon (Kevin Zegers) collapses after having sex with his fiancée. His symptoms seem too numerous to be explained by just one disease. Foreman and House suggest different diagnoses with each one arguing that his own respective theory better conforms to Occam's razor. But then Brandon's white blood cell count drops, proving both doctors wrong. At the clinic pharmacy, House theorizes that the pharmacist accidentally gave Brandon colchicine instead of cough medicine, which
After overhearing a conversation about a sick baby, House investigates the maternity ward and predicts an epidemic. After realizing the severity of the disease, Cuddy quarantines the maternity ward. In an effort to discover the source of the epidemic, House begins treating the children. However, when the kidneys of two of the children shut down, House is forced to test which drug caused the failure, resulting in one of the babies dying. Following an autopsy, the team discovers the presence of ec
Sister Augustine (Elizabeth Mitchell) arrives at the hospital with her hands covered in severe rash, which her fellow nuns think looks like stigmata and which House diagnoses as dermatitis caused by a dish soap allergy. When the antihistamines he gives her cause an asthma attack, House administers epinephrine, and she suffers a minor heart attack. House's team suspects that House made a mistake with the epinephrine, but when they try to find the source of her problems, she suffers hallucinations
A mother, Lucille Palmeiro (Stacy Edwards), collapses after a blood clot travels from her leg to her heart. After arriving in the hospital, she begins to vomit blood, causing House to expect a Vitamin K deficiency. House's team discover unused Ampicillin and frozen microwave burgers, supporting House's diagnosis. An ultrasound of Lucille's liver reveals cirrhosis and a cancerous tumor. The tumor is too large to resect but House orders the team to shrink the tumor with an injection of ethanol so