Dr. Kenzo Tenma, head of Neurosurgery at the Eisler Memorial Hospital in Düsseldorf, carries out a successful neurosurgery on a famous opera singer, but the hospital Director Udo Heinmann takes the credit during a press conference. Later, Tenma is saddened when he discovers that an operation on a Turkish construction worker was given a lower priority and subsequently died. The construction worker's widow blames Tenma for his death. When out with his fiancee, Director Heinemann's daughter Eva, Te
Dr. Tenma is able to save Johan's life, but Roedecker dies during surgery under Dr. Boyer. Boyer and Oppenheim scold Tenma, stating that the doctors had to scramble to cover for him at the last minute resulting in Roedecker's death. Oppenheim forwards his report to the director. As a news report states that flowers were left at City Hall and a decision for a new mayor is taking place, Director Heinemann states in a press conference that Roedecker died of a cerebral infarction and that they did t
The police arrive at Tenma's apartment and inform him that Director Heinemann, Dr. Oppenheim, and Dr. Boyer were found dead. When Tenma returns to Eisler Memorial Hospital, he also learns that the Liebert twins have disappeared. Following Director Heinemann's funeral, Tenma is informed by Inspector Egon Weisbach and Inspector Heinrich Lunge of the BKA that the dead men were poisoned by candy containing a muscle relaxant and Lunge suspects the doctor may be involved. Tenma considers returning to
Inspector Lunge questions Junkers about his involvement in the homicides and he becomes hysterical when Lunge asks who hired him. Tenma convinces Junkers to overcome his fear and confess his involvement, however, that night, Junkers finds his police guard dead and flees. Soon after, Tenma also finds the dead guard, poisoned by candy in the same manner as the hospital officials from nine years ago. He follows Junkers into a nearby construction site, and finds him with Johan Liebert, whose life Te
Nina Fortner is a bright university student studying law at a university in Heidelberg. She is seeing a counselor regarding strange dreams and has no memories of her life before the age of 10. She begins receiving poetic emails from an unknown person and decides to meet them. One day in a lecture class, she is overcome by fear and nausea at the mention of a family massacre. Meanwhile, Tenma is investigating the serial murders of middle-aged, childless couples and is searching for information on
With the help of Maurer, a local newspaper journalist, Tenma is able to track down the Fortners on the day of the twins' 20th birthday. The Fortners refuse to talk about the missing twin boy, but reveal that Nina has left to meet the "mysterious stranger" at Heidelberg Castle. Tenma drives to the castle where he saves Nina from a hired thug and takes her back home, trying to explain that she is Anna Liebert. Meanwhile, the thug, tied up with Tenma's necktie, fearfully meets his employer.
Tenma and Nina return to find Fortners and Maurer dead. The scene brings Anna's memories flooding back and she says that she shot Johan. Two detectives arrive at the scene and escort Tenma and Nina away, however Tenma becomes suspicious of them and he escapes with Nina. Back in town, Tenma finds that the detectives are legitimate and the thug at the castle was found dead. Nina, now aware of her past, slips away from Tenma. Inspector Lunge examines the scene, and finds a necktie that he suspects
Tenma returns to work at the hospital in Düsseldorf. Meanwhile, Lunge questions Eva, now a three-time divorcée, about the necktie he found at the murder scene, but she denies ever seeing it. Eva then pleads with Tenma to take her back, but he refuses and Eva threatens to turn him over to Inspector Lunge as she gave the necktie to Tenma years earlier. With the police on his tail, Tenma is forced to flee and he recalls the events that have led to his current situation. Five months later, Tenma lea
Five months ago, Tenma began rigorous firearms training with a former army veteran named Hugo Bernhardt, who was also taking care of an angry orphaned girl whose mother he shot and killed in Myanmar. During his time there, Tenma creates a new bond between the girl and the veteran, and later when questioned by Inspector Lunge, Bernhardt refuses to disclose Tenma's location.
While investigating the murder of a prominent councilman and his wife at the Springer Estate in Verden, Tenma encounters the petty criminal Otto Heckel and escapes with him. Heckel suggests that they could make good money by operating on wounded criminals, but also reveals that he knows the councilman's killer. They visit the killer who is remorseful, duped by a man called Erich into committing the murders. But before Tenma can extract any more information, Erich kills himself. In order to pay h
While investigating in the former East Germany, Tenma discovers that Johan was adopted by the Lieberts from an orphanage called 511 Kinderheim which is now abandoned. He contacts Hartmann, a former district official with the Ministry, who explains that the orphanage was an extremely harsh environment for the children, ruled by fear and violence. There, Tenma also encounters a boy under Hartmann's care named Dieter. When Tenma discovers Dieter's body is covered with bruises, he confronts Hartmann
Tenma learns that the orphans in 511 Kinderheim were part of a project to produce perfect soldiers through psychological reconstruction. However, during a power struggle, the 50 instructors and orphans were killed. Hartmann takes Dieter back from the hospital, and when Tenma visits Hartmann's apartment he realizes that Hartmann was at 511 Kinderheim and is now trying to reshape Dieter to be similar to Johan. At the ruins of the orphanage, Hartmann explains to Tenma that the battle was triggered
Tenma treats a local drunk after an accident, and then assists Dr. Schumann, the local doctor in treating the village residents. He visits an elderly woman who refuses to have herself examined when Tenma realizes that the woman has a subarachnoid hemorrhage, he performs an impromptu operation to save her. Meanwhile her son, a police officer, threatens to arrest Tenma after discovering that he is wanted for murder. However, Schumann and the villagers convince the police officer to let Tenma go, a
Workaholic Inspector Lunge is so busy investigating the case of a dead prostitute and her involvement with a politician that he shows no emotion when his wife and pregnant daughter leave him. When a key suspect in the case apparently commits suicide, Lunge is taken off all cases, so he decides to focus on catching Tenma. Meanwhile, the heavily alcoholic Eva Heinemann has casual sex with her gardener, but when she realizes that she is completely dissatisfied with her life, she burns her house dow
In Frankfurt, Tenma questions the now disgraced former Detective Mesner, one of the detectives he fled from earlier, over the murder of Fortners and Maurer. Mesner says it was Muller, the other detective, who murdered them and mentions "The Baby", a little person who is part of a right-wing nationalist organization who is looking for Nina. Meanwhile, Nina tries to find Johan, and acting as a prostitute meets Baby at the Candy Club, but he abducts her, and later also captures Tenma. At Baby's man
At Baby's mansion, Nina finds Ayse dead and then discovers that her captor, Goedelitz and all his men have been murdered. Meanwhile, General Wolf's men take away Tenma and Dieter, who was captured earlier. On the way, Tenma enables Dieter to return to Frankfurt to warn the Turkish community of the plot. Tenma meets Wolf who accepts his role in the origins of Johan whom he found cold and starving to death with his sister near the Czechoslovak border. He then says that Johan has killed everyone wh
Instead of meeting Johan, Tenma heads to the Turkish portion of Frankfurt to warn the residents of the neo-Nazi plot. Meanwhile, Nina confronts Baby while he is having dinner, but he refuses to disclose the location of the planned main fire. Numerous small fires are started, however they are relatively easy to extinguish. Nina finds and rescues Dieter and Heckel, who says the main fire will most likely be set near the wharves. At the river, Nina and Dieter find a neo-Nazi in a chemical warehouse
Mr. Rosso, the owner of an Italian restaurant where Nina used to work as Anna Liebert, picks her up after questioning by police. She recalls the time she spent working in the restaurant and took marksmanship lessons in the afternoons. When challenged by Nina, Rosso admits that he used to be a professional assassin. She leaves and continues her search for Johan.
Searching for an insight into Johan's personality, Tenma visits Dr. Rudy Gillen, a fellow student and academic rival at University who is now a practicing criminal psychoanalyst. Gillen intends to turn Tenma over to the authorities, but consults with one of his criminal patients in prison, Peter Jurgens. After the prisoner says he committed a murder for an unknown person and directs Gillen on where to find evidence that proves Johan exists, Gillen assists Tenma to escape.
Tenma and Dieter hitch a ride with an elderly couple on the way to Freiham. Tenma wonders if the couple plan to turn him in when he realizes that the husband is a suspicious former police officer. He used to think that he could tell a criminal by their looks, but realized that it was not possible after his son committed a murder. The husband confirms that Tenma is a wanted criminal, however he believes that Tenma is innocent.
In Nice, the former detective Muller, who with Mesner killed Nina's foster parents, is newly married and enjoys a good life. He hires a private detective to investigate the whereabouts of Tenma, Nina and Mesner, but when the detective arrives he is shot by Muller's bodyguard Roberto, who is working for Johan. Muller realizes that he was used to lure Nina into a trap, and Roberto takes Nina, promising to take her to Johan despite Roberto's plan to kill Nina, and leave her with his subordinates. H
Lunge determines that the murder of a wealthy, middle-aged, childless couple does not fit the usual modus operandi of the serial murders, but uses it as an opportunity to lure Tenma to a trap. He actually suspects the nephew who stands to inherit their estate. Tenma visits the murder scene and also realizes that it is a copy-cat murder. Lunge catches Tenma in the house, but before Lunge can arrest him, Lunge is critically wounded by the nephew, the real criminal. As he lies bleeding, Lunge still
Eva Heinemann is arrested for public drunkenness and is also homeless after not paying her rent. She hooks up with Roberto, with whom she was drinking the night before her arrest. After realizing that she has photos of Johan, Roberto presses her about her link to Johan. Eva reveals that she saw Johan at the construction site in Düsseldorf on the night Junkers was killed. Roberto prepares to kill her.
To save her life, Eva offers Roberto the photos of Johan in exchange for information about Tenma's location. Roberto tells her that Tenma is currently treating a wounded mob boss at a country house near Füssen. Roberto and Eva approach the country house and Roberto kills the bodyguard who just manages to warn his boss before he dies. Roberto doesn't trust Eva and shoots her in the leg, and as she lies bleeding, she tells Dieter to run as Tenma would never come to save her. However, Tenma arrives
In Munich, Karl Neumann is one of the students who reads passages of Latin on Tuesdays to the elderly, blind and very wealthy Hans Georg Schuwald. Karl encounters fellow student Lotte Frank, who does housekeeping for Schuwald and whom she is using as the subject for her research paper. Karl agrees to join her in tailing Schuwald when he goes out late at night. They discover a woman claiming to be Margot Langer, the mother of his illegitimate son, who turns out to be Karl, however the student who
Schuwald hires a private investigator named Richard Braun to determine the truth behind Farren's suicide. During a discussion with his psychotherapist Dr. Julius Reichwein, Braun confirms something is amiss with the death. Meanwhile, Johan offers to help Karl reconcile with his long lost father, whom he believes is Schuwald. When Karl and Lotte take Schuwald to visit a lake that is now a construction site, Johan arrives and paints a verbal picture that convinces Schuwald that he is standing on t
Braun tries to reconcile with his ex-wife while dealing with his past alcoholism and again visits Reichwein, and begins to suspect Karl is involved in Farren's death. Meanwhile, Karl is about to formalize his adoption with his foster parents, but Johan intervenes and enables Karl to reconcile with his real father, Schuwald.
Schuwald informs Braun that the case involving the suicide of Farren is closed, but Braun becomes suspicious now that Karl and Johan are caring for Schuwald. Braun decides to review all his unsolved homicide cases, but is haunted by the case that caused his alcoholism and error of judgement which caused his dismissal from the police force. His investigations all seem to have a connection with Schuwald and when he presents his findings to Reichwein, the doctor also reveals that Gillen believes th
Braun begins to observe Johan and investigate his origins, while Reichwein asks Gillen to question his criminal patient Peter Jurgens about Johan. Meanwhile, Braun discovers that the real Johan Liebert died at the age of two. When Gillen shows a photo of Johan to Jurgens, it triggers painful memories and he promptly commits suicide with Gillen's pen. At night, Johan visits Braun and manipulates him into a state of deep regret. Johan then offers Braun a bottle of whiskey on the rooftop of a build
Reichwein muses over the death of his friend and patient Richard Braun with Gillen who suspects foul play. Reichwein retraces Braun's last steps and determines his death was not an accident, but a murder. Two thugs are hired to kill Reichwein, however he survives. Later, Roberto attempts to kill Reichwein at his office, but he is saved by Tenma who has been shadowing him.