Black Jack is given a chance to redeem his medical license, by treating the son of Detective Takasugi who has Paget's Disease. The operation is a success, but Jack refuses to comply with the bureaucratic registration process and is arrested for practicing without a licence. During Black Jack's imprisonment, a former patient, the Italian billionaire Mr. Boccherini, begs Black Jack to save his grandson, but the head of the Japan Medical Association refuses to release Black Jack despite the billion
Black Jack, still holds a grudge against his father for walking out on him and his mother Mio after they were caught in an explosion. However, he responds when his wealthy father, Kagemitsu Hazama, contacts him for the first time in 21 years. Kagemitsu offers money and a partnership in his syndicate if Jack will perform plastic surgery on his second wife, Renka, who was burned in a fire. His father instructs Jack to make her "The most beautiful woman alive". When the bandages are removed, his fa
Pinoko, refuses to believe that Black Jack is dead and continues to dig through the rubble of their bombed out house. For a while, she lives in the diner owned by Jack's friend Tetsu, but later reluctantly agrees to be adopted by a family that runs a local hospital. It is then revealed that Black Jack survived the bomb blast set by the assassin Benitokage, thanks to help from his friends, Toriton the killer whale and the father and son fishermen. Jack remains in hiding to prevent placing Pinoko
Black Jack and Pinoko fly to Europe to track down Dr Kreutzer, a man that Jack recognized in the photograph he found at Honma's clinic. While at a hospital run by Dr. Kreutuzer, Jack befriends a little girl named Suzie. He enters the hospital where he finds that Dr. Kreutzer has been in a persistent vegetative state for two months after a car accident. The hospital controller, Mr. Devon, asks Jack to impersonate Dr. Kreutuzer and perform an operation on a cancer patient. At first Jack refuses, a
After encountering Dr. Stein at Kreutzer's hospital, Black Jack follows Dr. Stein to his hospital in Germany where he is a leading expert on prosthetic limbs and organ transplants. Jack encounters a colleague, Dr. Konomi Kuwata (a.k.a. Black Queen) who mentions that Dr. Stein is about to perform an operation that would attach an experimental robotic arm to the boy Triton, an aspiring pianist who has Ewing's sarcoma. Jack fails to get any answers from Dr. Stein, but he does talk to the boy who wo
With the help of Dr. Ayako Nishikawa whom he met during his encounter with Dr. White, Black Jack is offered a lift to England by riding in the Sky Hospital owned by Dr. White, a military aircraft converted into a fully functioning airborne clinic. During the flight, a group of militants hijack the plane, planning to turn it back into a fighting craft to help their own people in Taranistan. The passengers and crew of the plane resist the terrorists, but one of the militants detonates a stun grena
Black Jack and Pinoco arrive in a middle eastern town after leaving the damaged Sky Hospital. While there, they befriend a Japanese man named Aritani who is there on business. Later that night Black Jack is arrested and accused of murder, but Pinoko finds Aritani who provides an alibi for him. Jack offers to repay the favor with a free treatment if ever required. Later, Aritani returns to his office in Germany where he is pressured to take the fall for his company which was redirecting money ill
Black Jack finally arrives in England searching for Dr. Stein when he hears of a man who's been in a coma for 65 years but has not aged. Dr. Stein wants to analyse him seeking information about eternal youth, however the patient's niece has hired Dr. Kiriko to end his life. Instead, Jack successfully operates on the patient who regains consciousness, but begins ageing rapidly and dies. Shortly afterwards Dr. Stein tell jack that it was him who urged Dr. Honma to try organ transplants on Jack 21
Black Jack and Pinoko travel to New York. Dr. Bart, now the head at Dr. Jorujyu's hospital, asks Jack to help him operate on his mother, Catherine Bart, because she has Honma's Hematoma. Jack, remembers his mentor's words not to get involved in that disease and refuses. Years earlier, the medical community accused Dr. Honma of conducting a live experiment on a patient with the rare disease causing him to resign. Later, Jack locates the clock which appears in the old group photograph just as Beni
Black Jack survives the shooting because his mother's pendant stopped the bullet. He operates on Dr. Bart’s mother, Catherine, and discovers that she has a Type Hydra artificial heart which keeps beating even when it is extracted from the host. Jack replaces the Type Hydra with another artificial heart and saves her life. They discover that the Type Hydra was designed by Jack's father, Hazama Kagemitsu, through a microfiche that was inside Mio's pendant. Catherine tells Jack how his parents met
Black Jack and Pinoko travel to Canada and arrive at Dr. Jorujyu's lakeside cabin. Jack is shot at by the doctor's daughter Yuri, mistaking him for her brother. Dr. Georges is seriously ill, and Black Jack diagnoses that he has mediastinal pneumonthorax causing air to leak into a body cavity. Yuri's brother arrives, and is he none other than the infamous Dr. Kiriko, who has been unable to save his father and plans to euthanize him against his sister's wishes. Dr. Kiriko reveals that his father a
Black Jack and Pinoco travel by train to find Dr. Jorujyu's research lab however, Benitokage continues to pursue him with her henchman Souryu. Benitokage tracks them through the snow, but during a violent confrontation she is injured and Jack decides to rescue her and treat her wounds. In Dr. Jorujyu's cottage cellar, Jack finally stumbles across a document about the mysterious Phoenix disease. The weather worsens with a heavy blizzard as Benitokage regains conscious. She takes Pinoco hostage an
Ten years ago in Africa, the twins Niko and Al were orphaned by floods, but only Niko is adopted. In the present, Black Jack and Pinoko arrive in Africa searching for Dr. Kuma and encounter Sharaku and his father. Jack is concerned with Pinoko's safety and requests that Sharaku's father send her back to Japan with Sharaku which devastates Pinoko. In the street, Pinoko meets a Al who is now a grocery boy and later encounters his twin brother Niko who is caring for is adopted mother. Her son was k
Black Jack and Pinoko arrive in a remote village in Africa looking for Dr. Kuma, however they find that many villagers are dead from ailments possibly caused by Phoenix disease. Jack and Pinoko then walk to Arnol Village where they befriend a local girl, Mary, who takes them to Dr. Kuma. Mary's mother falls ill and is rescued by Jack, but he collapses dues to a bite from a tsetse fly. Fortunately Dr. Kuma saves him and reveals that he was an apprentice of Dr. Honma at the time the Noir Project a
Black Jack returns to aid his comatose father and be a part of the family, but it is a ploy by his stepmother Renka's father, Zen Mantoku, to obtain his mother's pendant containing the microfiche. Jack refuses, but the organization's henchmen kidnap Pinoko and lure Black Jack in to a trap. Suddenly, Benitokage appears and saves Pinoko and Jack, but another henchman knocks them both out and takes Jack to meet Zen Mantoku, head of the organization and also Renka's father. Mantoku asks Jack to join
Black Jack prepared to return to Japan with Pinoko when he is requested to go to the Sky Hospital. Jack finds the only patient is Zen Mantoku, who suffers from the Phoenix disease because he and the other members of the Noir Project were injected with B.O.P. Jack agrees to assist Dr. White for 1¥ billion to develop a cure. However, Renka, aggrieved by the loss of her husband and daughter, and fact that Black Jack gave her the face of her husband's former wife, secretly plots to kill Jack and obt
Black Jack tells Dr. White to change the course of the Sky Hospital to the North Pole while they are told that the Doctors from around the world are working to cure to the Phoenix disease. Dr. Kuma reveals that they only have 21 hours to find a cure or die before a Nuclear Missile will be fired to destroy the Virus and all those infected. Renka boards the Sky Hospital planning to kill Jack, but her father, Zen Mantoku, tries to stop her and they shoot each other. Zen Mantoku dies but Renka survi
Although Jun is in wheelchair, he tells his Internet friend Tom he can play baseball. He did this because he was envious of Tom's stories of living on a ranch and helping out with all of the chores there. When Tom is about to visit, Jun asks Black Jack to heal his weak heart. The price is too high, and Jun breaks off his friendship with Tom instead. When Tom finally arrives, Jun learns that he is the young, blind inheritor of a large company. Tom offers to pay Black Jack's fee for healing Jun, a
Black Jack is forced to take Pinoko to a local clinic for digestion medicine, and comes to assist Dr. Kowa, a country doctor, in a thyroid operation. Black Jack is extremely impressed by the friendliness and respect Dr. Kowa is treated with by his patients, especially since he can tell Dr. Kowa is an unlicensed doctor. In the end, Dr. Kowa goes back to school.
Tetsu, the owner of Black Jack's favorite cafe, tells the story of how he was a famous pickpocket chased constantly by a police detective. The detective desperately wanted to catch Tetsu red-handed, but during a chase, Tetsu is injured in an accident involving sheet glass and loses two fingers. The detective blackmails Black Jack into performing surgery to reattach them, hoping to continue as before, but Black Jack covers for Tetsu, and in the episode Tetsu returns the favour when the detective
Kumiko loses sight in one eye due to glaucoma. Black Jack implants a cornea, and Kumiko starts seeing the donor's last sight; a man reaching towards her. Pinoko thinks the man is a murderer and begins a rescue effort, but it turns out the vision is of the donor's fiancee in his last, desperate attempt to save her.
Pinoko meets Tinq, a boy her age, and tried to have an adult relationship with him, much to Sharaku's horror. Tinq has a strange condition, though; his organs are reversed, and Black Jack with Pinoko's help undertakes an operation to save his life. It turns Pinoko has been trying to make the Doctor jealous, as he is the one she truly loves.
Black Jack meets Kiyomi, a pretty young physician, and the only doctor on her island. Kiyomi falls in love with Black Jack, but he knows he's not worth her giving up her life on the island with so many people depending on her. Then, Kiyomi is injured in a landslide and is saved by Black Jack, only to wake up and find him already gone.
A genetically-enhanced deer, Nadare, is attacking forest workers. In the past, the deer was befriended by a young doctor and treated as his own sibling. Wishing Nadare was intelligent enough to talk back, the doctor convinces Black Jack to move Nadare's brain from his skull to his chest, allowing it to grow and make him smarter. In the present, the doctor who owned the deer must stop Nadare who, out of control from his own intelligence and emotions, attacks his fiancé. They drive Nadare off, and
Black Jack thinks that he may have cholera, so he quarantines himself, leaving Pinoko to take care of a patient at the clinic for three days. Thinking he is in the clear after the incubation period has passed, Black Jack returns to the clinic and performs an operation, only to become extremely sick in the moments afterward. Black Jack thinks he has cholera after all, but it turns out to be Pinoko's special medicine that caused the symptoms.
While hearing Pinoko talk about the abacus, Black Jack remembers when the teacher and father of Eiji, a boy, came to see him a long time before. Eiji dreamed of being an abacus champion, but he couldn't move his hands. Black Jack operated to fix them, but when his hands cramp up in a competition, reverts to using the abacus with his tongue.
Black Jack, Pinoko and several rich men are trapped in an underground, disaster-proof bunker, where the oxygen is being sucked out. BJ breaks through the wall with a scalpel and cuts a wire, finally releasing them when all were on the verge of death. The men had promised him money to free them, then tried to renege. Fortunately, Black Jack has their promise on tape.
Black Jack and Pinoko investigate a mysterious plague in Australia. They become separated; Pinoko befriends an Aussie, Black Jack walks for days. Black Jack contracts the deadly plague, and realizes it is actually a parasite (an Echinococcus, a tapeworm, which causes echinococcosis or hydatid disease). He removes it by performing surgery on himself inside a plastic tent.
Black Jack takes on a case of Sono, a young girl who is sensitive to light and has a weak heart. Her father wants her to become better at all cost so she can become the head of the family. The family's main focus is ikebana so Sono is pushed to the brink of death to make the ultimate ikebana for her recital. When Sono almost dies trying to go outside to see wildflowers in their natural beauty, Black Jack tells her father she is being pushed too hard. Sono tells Black Jack she will die anyway so
There is a massive strike of Doctors in a hospital, where a little kid asks a doctor to cure his father but due to the strike the doctor refuses. Then the kid finds a young lady that tries to get help. Finally trying to take the Kid's father to another hospital a thunder makes a tree to fall making impossible to keep going, while they find the doctor who refuses the operation. Black Jack enters in action and decides to operate the sick man in a countdown before a Tree falls on them. A Tree fell