Ray Langston fights for his life after being stabbed by psychopath Nate Haskell, after he helped Ray and the CSIs crack the case of Dr. Jekyll. But while recovering, Ray remotely works from the hospital on his next case. CSIs try to catch an anti-government bomber who is responsible for a series of explosions at a funeral for Officer Clark who was killed by Dr. Jekyll (after events in "Meat Jekyll"). Young activist Jason McCann may hold a vital clue to the bomber's identity.
A woman is attacked by a shark inside the pool at a day club at the Golden Nugget Casino. Initial suspects include ex-con "Drops", jewelry thief Anya Sanchez, and the Golden Nugget's owner Earnest Boozell, who suspects that rival club owner Danny Macklin arranged the murder to draw customers to his own casino. Boozel is upset when he discovers Catherine is investigating the case, as he and her father, the late Sam Braun, were rivals. Later, a scuba diver, revealed to be the aquatic veterinarian
After the CSIs discovers a member of the Vampire Cult found tied to a fence with multiple slash wounds and his dismembered head on a pike, Ray and Nick plunge into a world of creeds and a legendary rivalry between vampires and werewolves, as they investigate whether or not mythological bigotry was involved. At a hotel convention, an armory dealer provides a clue to the type of weapon used to behead the victim.
Based on the first Level 26 novel, Dark Origins, Sqweegel is the forensic-proof serial killer who kills people who have secrets and tries to get them to confess to something they have done in order to stay alive. One of the victims includes socialite Margot Wilton, who for many years has hidden her dark secret related to her deceased son. Margot's lawyer Oscar Goodman prevents the CSIs from questioning Margot, and from entry to her house just as the killer strikes against her a second time. Alth
Nick and Sara investigate a decomposed body in a house of a hoarder. However, they soon discovered that its occupants have hoarded four more dead bodies over the years.
A body of a college student is found in the desert and appears to have been punctured by dinosaur teeth, which was later discovered to have come from the teeth of the animatronic T-rex in the touring Walking with Dinosaurs − The Arena Spectacular live production. Meanwhile, the shooting of a business man leads the CSIs to two teen murders that happened five years ago, and a missing girl with a ransom involved, but no guarantee that she would be found alive.
The CSIs try put a body back together, after it is literally shredded in an industrial shredder. As they gather up the "parts", they discovered that the victim dined on his last meal of a unique clam chowder, consisting of clams, carrots, celery and a human ear, with chopped credit cards as garnish. The "garnish" was obtained fraudulently in a name of a Las Vegas businessman, who operates an anti-fraud service. Also, Ray receives a kidney bean and a "thinking of you" letter from Nate Haskell, st
A young couple swimming in a local pond noticed an awful stench coming out of the water, just before discovering a dead body float up. He was one of several sources for a newspaper article of fracking and illegal natural gas dumping, found dead during the course of the CSIs' investigation. Another suspect was burned to death after flicking a lit cigarette into a well, not knowing that the water was infused with methane. The murderer is found dead, a victim of a hit and run, and they are unable t
Ray, Catherine, and Nick try to figure out if it was murder or suicide when a man is found dead after falling from an upper floor of the Eclipse hotel; two young women, who were looking for "eligible bachelors", were the witnesses, but also the suspects. Across town, Sara and Greg investigate a case where an elderly woman falls through her table and her husband dead in the shower; the only two witnesses to the crime are an uncooperative cat and a parrot who was unable to talk - or so they believ
The wife of an FBI agent is murdered at a local supermarket, and her kids had disappeared. The agent had been chasing a serial pedophile, who is suspected of kidnapping his children. His demand to immediately find the suspect and bring closure to the case clashes with Brass' method of not getting ahead of the evidence.
A prostitute is found dead at the same site where a staged photo of the same dead person was taken and posted on a website days earlier, as part of an unusual "bucket list" for a trio of college alumni, which also includes the kidnapping of Carrot Top. Hodges suspects that his Triumph motorcycle that he recently bought was built with spare parts at a junkyard - one of them from a bizarre deadly crash involving a motorcyclist and two buses.
While the team searches for a serial killer who murders his victims with an electric chair, Greg falls for classic film noir femme fatale burlesque dancer Rita Von Squeeze (aka Ellen Whitebridge) who may be connected not only to this case, but also to the 1946 murder of songbird Agnes LaPlouffe and a mob hit orchestrated by Bugsy Siegel.
A night full of celebration ends with a bang when Dr. Lambert the director of a scholarship foundation for the deaf is killed by a deadly car bomb, prompting Sara to interrogate deaf college students and faculty including Professor Julia Holden, Gil Grissom's former lover. Sara's mother-in-law Mrs. Betty Grissom has a grudge against Sara, due to her not being with her son Gil while on an expedition in Peru.
When a couple of elderly ladies discovered a dismembered body amongst the donations at a thrift shop, the CSIs investigate the gruesome murder of a high-powered, widowed lawyer. Meanwhile, Ray faces that it is time to move on from his old life when his ex-wife Gloria Parkes comes to Vegas.
While Langston testifies against Nate Haskell, Nick is warned that he is in danger, after discovering that his front gate was rigged with an anti-personnel mine, but the caller cannot tell him who or why without putting himself in even more danger. Later, Catherine, Vartann and Nick are trapped in a rigged warehouse, with only 15 minutes to defuse the bomb amidst a series of triggers, without the assistance of the bomb squad or other officers. At trial, Haskell represents himself pro se, questio
As Ray and Brass are still scratching their heads on how Nate Haskell managed to escape police custody following his trial, a "corpse" that Phillips was prepping for an autopsy wakes up and walks out of the morgue. The CSIs suspect that his "death" was a result of drugs he was administered as part of a psychoactive drug study conceived by Dr. Aden. The CSIs find two other people who must get help before it's too late.
Following a prison riot, the team investigates the murder of a cop, Vance, who was incarcerated for murdering his wife, but believed he was framed. During a cell search, Nick also uncovered a notebook that included a list of names that Vance felt was at fault - including Brass.
For the CSIs, "the cycle" consists of a homicide, a suicide, an accidental death, and a death by natural causes in a single shift. When the first three happen, the CSIs compete to complete the cycle by finding a death by natural causes - even if the cause looks obvious on the outside, forensics would say otherwise. Cases included a gamer who died while playing an online game, and a man found dead in his pool following a burglary. They must also deal with a new employee from Los Angeles, who make
Ray and Sara visit Grissom's friend, "Lady Heather", to solve a strange case involving a woman who is mauled to death in the backcountry by a mountain lion; she was actually behaving like a cat herself. Meanwhile, Nick and Robbins deliver a baby through an emergency Caesarean section, after its 17-year-old mother died after hanging herself; Nick and Brass investigate after determining that she died as a victim of severe cyberbullying. Later, Lady Heather gave a word of advice to Ray about Nate H
As the notorious Nate Haskell sends a threatening video to the father of one of his brides threatening to kill her, the CSI team must catch him. Sofia Curtis returns to help out, as she is now the Deputy Chief.
In Los Angeles, Ray's ex-wife Gloria Parkes is kidnapped and Haskell leaves a message written in blood drawing the CSI team to Los Angeles. While the LAPD (where Conrad Ecklie's daughter, Morgan Brody, works in its SID division) was less than happy that another jurisdiction was interfering in their case, Nick found himself arrested while pursuing not only Haskell, but also Ray, who's gone rogue while on the hunt for Haskell.
Ray has tracked Haskell back to his childhood house in Nevada. Desperate to save his ex-wife Gloria before it is too late, Ray prepares to settle his score with the notorious "Dick & Jane Killer" once-and-for-all, leading to Haskell's violent death. Brass and the CSIs would not only determine if Ray's killing of Haskell was "self defense or murder", but also uncover more on the creation of Haskell's psychotic persona.