Bree tries desperately to keep what happened to Alejandro a secret from Chuck who is growing increasingly suspicious. Carlos becomes short tempered and depressed while he struggles with his guilt, and Gabrielle convinces him to confide in his priest. Ben Faulkner, a new neighbor, meets Renee; she is immediately interested in him, but he rebuffs her. Meanwhile, Susan withdraws from her friends because of what happened to Alejandro. Tom and Lynette go to great lengths to hide their separation from
Gabrielle struggles when Carlos has no interest in sex and attempts to spice things up with him. When her attempts fail, she tells him she just wants things to go back to normal, Carlos snaps and yells that he will "never be normal again". Susan seeks out a punishment for feeling guilty, purposefully committing obvious petty crimes to get arrested. When she finally is, Carlos comes to bail her out and they confide in each other about how they feel they are the only ones struggling. Renee attempt
Renee helps Lee when he has a problem with Jenny; Susan and Carlos begin to spend time together due to their guilt but Mike begins to get suspicious; Bree becomes convinced Chuck sent the letter to her so she and Gabrielle investigate; Lynette grows suspicious of her sister Lydia and her new fiancé.
Lynette discovers Tom is dating; Bree attempts to comfort Danielle after her husband leaves her; Susan clashes with an art teacher named Andre, who she had hoped to impress; Gabrielle's rebellious attitude towards the leader of the PTA leads to her being put in charge.
Tom and Lynette visit a couples counselor about their separation; Bree tries to help the city council regarding the homeless; Carlos is in a guilty situation; Susan is horrified about Andre requesting students to be naked in the next class; Gabrielle is having difficulty setting up a school event.
Susan is appointed as Andre's intern and ends up watching his son; Lynette tries to outdo Jane and lies about making Penny's costume; Carlos speaks to a sponsor from A.A. about his blackout; the housewives are in the woods with the shovels, but the body they buried was mysteriously dug up; Renee gets romantic with Ben.
Bree is stunned when she learns who dug up the body of Gaby's stepfather; jealousy rears its ugly head when Lynette begins to spread untruths to daughter Penny about Tom's new girlfriend; Gaby and Carlos must convince Lee and Bob that Juanita and Celia aren't the bad seeds that they used to be when they want to name them in their will as guardians; and Susan desperately searches her inner self to find what inspires her in order to better her art and impress her hard-to-please art teacher, Andre.
Detective Chuck Vance begins harassing Bree as his suspicions about her involvement in the disappearance of Alejandro grow; after using the murder of Gaby's stepfather as inspiration for her art school projects, Susan must find a way to graciously decline art school teacher Andre's (Miguel Ferrer) invitation to display and sell her paintings at a gallery showing; when Carlos's drinking gets in the way of his ability to work, Gaby goes to The Office in an effort to save his business from losing a
Chuck interrogates Susan, Lynette and Gabrielle about Alejandro's disappearance; Gabrielle goes on a desperate search to find Carlos; Lynette tells Tom a horrible secret; a drunk Bree reveals her past and present details, and then goes to a motel room where she sits and has a brief conversation with Mary Alice while having her gun set on the table.
While searching for Carlos, Gabrielle is shocked by a news report on Chuck Vance's death; Susan informs Mike she is leaving for New York when, in fact, she is actually leaving for Oklahoma to visit the late Alejandro's family.
While in Oklahoma, Susan finds out from the late Alejandro's family that his stepdaughter, Marisa, was abused by him just like Gabrielle was; at a bar, Bree finds out something surprising about her new boyfriend; Gabrielle has some difficulty with Carlos's potential clients; Mike catches Ben doing some illegal activities in his real estate project.
Karen McCluskey finds out about Bree's sex life and interferes, Bree bumps into one of her many conquests unexpectedly, Gabby shares her past with the widow of Alejandro, and after introducing them, Renee ends up paying the price when the date between her hairdresser and Lynette doesn't go well.
Since Bree is spending time meeting men at the bar and/or in bed, the only person who can help her is her ex-husband, Orson Hodge, the man who ran over Mike Delfino years ago; Susan finds out that Julie is pregnant; Gabrielle tries to handle a situation at school involving her daughter, Juanita.
Susan discovers the identity of the father of Julie's baby, and Orson makes it his duty to nurse Bree back to health. When Mrs. McCluskey throws Roy out of the house, Gabrielle takes him in and is reluctant to help get them back together when he proves to be an invaluable disciplinarian to her kids. Meanwhile, after getting used to her alone time, Lynette is furious when Porter and Preston are evicted from their apartment and try to move back home, and Mike informs Renee of Ben's dire circumstan
After Lynette refuses to help raise Porter and Julie's baby, Susan offers to assist by setting up a nursery; Orson tries to get Bree to go to Maine with him; Ben's loan shark sets out to destroy Renee; Karen swears Gabrielle to secrecy; Orson, who knows what happened to Alejandro Perez, sends a letter to the authorities.
The police read the details on Alejandro's death; Mike is forced by Susan to tell the police about Ben's loan shark; Carlos's strange behavior about money concerns Gabrielle; at Penny's birthday party, Jane tells Lynette some news; Bree is asked by Karen McCluskey to help her commit suicide; Mike is gunned down.
The funeral of Mike Delfino leads to the ladies remembering how he impacted their lives; Bree is shocked when the police call her in for questioning regarding the murder of Gabrielle's stepfather; Lynette realizes she must fight for her marriage; Gabrielle agrees to let Carlos quit his job to help people.
Bree is not so sure about Andrew's upcoming marriage; Gabrielle tries to find work in order to keep up her lifestyle; Lynette attempts to win back Tom; Susan finds a way to help M.J. through his pain; Ben and Renee get engaged.
Carlos gets concerned about Gabrielle's new job; a secret of Mike makes Susan suspicious; Bree needs a lawyer's help in order to get her charges of Alejandro Perez's murder cleared; Jane works hard to make sure Tom and Lynette's divorce goes through.
With Mike gone, Susan attempts to build a car for MJ's father-and-son school soapbox derby; Bree's attorney, Trip, learns of her previous drunken sexual spree and needs her to come clean about it in order to help strengthen her case; Lynette tries to cause some negative friction between Tom and his girlfriend, Jane, by flirting with his boss and getting him to pile more work on her estranged husband; Gaby is furious with Carlos when he tries to poach one of her rich, personal shopper clients (Do
In the penultimate episode leading into the two-hour finale of this landmark series, as her trial nears, Bree begins to fall for her attorney, Trip; Susan becomes concerned when Julie doubts Porter's commitment to be a hands-on father to their unborn baby; as Tom gets closer to being transferred to India for his job - thanks to Lynette - she begins to have second thoughts and tries to convince his boss to rescind the move; and the ladies are shocked about Gaby's nonchalant attitude as Bree conti
Bree's trial finally comes to an end with a surprise confession. Tom takes steps to finalize his divorce.
Everything that begins must eventually end. This episode of beginnings and endings walks us both backwards and forwards as we take our final stroll down Wisteria Lane.