The Rugrats go on a vacation to Las Vegas in an RV, where they cause their usual mayhem. Meanwhile, Tommy searches for "kitties" (white tigers).
When Angelica and her parents go away for the weekend, Chas and Chuckie look after Angelica's cat while she is away and underestimate the difficulty of doing so. ---- Tommy and Chuckie fear "the Sandman" after a story while Chas is out at a party. Stu and Didi try to get them to fall asleep, but fall asleep themselves. Tommy and Chuckie then try to catch the Sandman, but end up catching Chas.
When Tommy saves a baby bird from a runner, he falls into a thorn bush and gets a cut, which frightens him. ---- The babies think that Chuckie has gotten bigger when his shirt shrinks in the wash.
The babies take part in a Western spoof to reclaim ice cream coupons from Angelica. ---- Tommy dreams that Chuckie and Angelica switch personalities—Angelica is more timid while Chuckie turns mean and bratty.
Angelica learns a curse word from the host of her favorite children's show, Miss Carol's Happy House. Not knowing what it means or how negatively her parents will react, she begins to use it in her vocabulary. ---- Jonathan looks after the babies while searching for ways to blackmail Charlotte.
The babies fear there is a "bad bug" in Grandpa's bed and attempt to get it out. ---- Grandpa takes the babies to a bingo game at the senior citizens' center. Note: This episode marked the final performance for David Doyle as Grandpa Lou and was dedicated in his memory. Joe Alaskey would succeed Doyle in this role for the remainder of the show's original run.
Angelica tells the babies that the police officers arrest bad people while Chas is dating a police officer. Chuckie accidentally breaks Chas' glasses and fears that he will be arrested. ---- Didi's brother and sister-in-law consider having a baby, and to prove it, they babysit the babies while Stu, Didi, and the other grown-ups leave for an opera. The chore, however, becomes harder than the sitters hoped it would be.
Chuckie's latest crush has an over-protective brother. ---- The gang goes to a pizzeria that resembles Chuck E. Cheese's and tries to get Angelica's tickets back from a pig that "stole" them. Meanwhile, Stu and Drew attempt to beat one another's high score at a Reptar pinball game.
Tommy is mistaken for another troublemaking baby with a big tooth, but he attempts to prove his innocence. ---- When Grandpa Lou takes the babies to Aunt Miriam's to play cards, the babies are convinced that she and her friends plan to eat Chuckie and attempt to protect him.
Chuckie is nervous about riding his new two-wheeled bicycle. ---- Stu and Didi accidentally leave Grandpa behind on a road trip, and Tommy and Chuckie try to give Grandpa a chance to catch up.
Tommy gets hiccups, and the babies' attempts to scare him do not cure him. ---- A change of season makes the babies think that the trees are ill, so they apply whatever remedies they think of to them.
The babies go down to the basement to retrieve Chuckie's robotic Reptar toy. ---- The babies attend Timmy McNulty's birthday party, where girls are left out due to cooties.
While Didi and Stu go on an anniversary vacation, Tommy and Angelica stay at Chuckie's house, where Chuckie learns about his ancestors. Meanwhile, Didi starts to feel seasick, and the cause is eventually revealed to be pregnancy.
The babies try to defend a live turkey that Grandpa wins from being Thanksgiving dinner; Stu and Drew try to watch football, Didi and the ladies try to find food for dinner; and Angelica wants to hold a parade.
The babies go out for pizza.
Tommy is mistaken for a troublemaking baby.
A poker game at Aunt Miriam's house.
Chuckie gets his first bike.
The adults leave Grandpa at a gas station.
Tommy has the hiccups.
Falling leaves concern the babies.
The babies venture to the basement.
The Rugrats attend a birthday party.
Chuckie becomes jealous of Tommy after hearing about his family tree.
The kids try to free the live turkey intended for Thanksgiving dinner.