Stardate: 46379.1. Commander Benjamin Sisko and a new crew of Starfleet and Bajoran officers take command of an abandoned Cardassian space station and make an incredible discovery that will change the galaxy and Sisko's future. A new crew is assigned to a former Cardassian space station: Deep Space Nine. It is a joint Federation/Bajoran force, with Commander Sisko in charge, but his life is dramatically changed when he is declared the Emissary to the Prophets by a Bajoran priest.
Stardate: Unknown. Kira finds her loyalties divided when a Bajoran extremist wanted by the Cardassians comes to the station with questionable intentions.
A Bajoran terrorist with ties to Kira arrives on Deep Space Nine and is pursued by the Cardassians. Garak, a mysterious Cardassian tailor who lives on the station, assists in uncovering what he is up to.
Stardate: 46423.7. A deadly virus created by the Bajorans 18 years earlier inadvertently breaks loose aboard the station, and prompts a race against the clock to find a cure.
Stardate: Unknown. When O'Brien befriends the station's first visitor from the Gamma Quadrant, he learns that the mysterious alien is on the run from determined pursuers.
Stardate: 46531.2. Vash arrives from the Gamma Quadrant as Q plagues the station and an unknown force threatens to destroy it.
Stardate: 46910.1. Jadzia Dax is charged with a murder that her symbiont's previous host Curzon allegedly committed. Now an extradition hearing may decide whether Jadzia can be held responsible for the actions of a previous life.
Jadzia Dax is arrested for a murder allegedly committed by Curzon Dax, a previous host of her symbiont. An extradition hearing is held to determine whether Jadzia can be held liable for Curzon's actions.
The Wadi from the Gamma Quadrant are to make first contact and decide to visit DS9. When they catch Quark cheating they let him off by playing a special game.
Stardate: Unknown. Grand Nagus Zek, the leader of Ferengi society, comes to DS9 to oversee the introduction of a Ferengi business presence in the Gamma Quadrant and announce Quark as his successor.
Stardate: Unknown. A wanted man from the Gamma Quadrant with questionable motives reveals to Odo stories about other "Changelings," which may hold clues to Odo's mysterious origin.
Stardate: Unknown. Sisko, Kira, and Bashir take Kai Opaka through the wormhole for a brief excursion in the Gamma Quadrant. But when they crash-land on a desolate planet, they find a divided, warring penal colony where no one ever dies.
The spiritual leader of Bajor, Kai Opaka, travels with Sisko, Bashir and Kira on a trip to the Gamma Quadrant, but is stranded on a world where the dead are resurrected.
Stardate: 46844.3. Kira finds herself in a difficult moral situation when her job demands she force an adamant Bajoran man from his home in the name of progress.
Kira has to deal with a stubborn farmer (Brian Keith) who refuses to leave his home even though it is slated for demolition.
Deep Space Nine is put in jeopardy when the crew's thoughts manifest themselves, and such figures as Rumpelstiltskin appear.
The Federation ambassador from Betazed, Lwaxana Troi, visits the station, and develops an affection for Odo. Meanwhile, data from a mysterious Gamma Quadrant probe causes system failures on DS9.
Tensions rise between the DS9 crew members after they are telepathically imprinted with the memories of participants in an alien power struggle.
A visiting Cardassian, Marritza, may in fact be the notorious war criminal Gul Darhe'el, butcher of Gallitep labor camp, and Kira is determined to bring him down.