Murdoch enlists the help of Nikola Tesla while investigating the inexplicable murder of the newly crowned Miss Toronto Electric and Light, who is electrocuted by an insulated switch at a public demonstration on the dangers of alternating current. Crabtree becomes romantically involved with one of the suspects, Edna Garrison.
A murderer taunts Brackenreid by sending him the bodies of a lawyer and a judge, along with a note claiming he will be next. Murdoch's impressive detection skills are noticed by Chief Constable Stockton, who subsequently interviews him for the position of Inspector at another police station.
When African American boxer Amos Robinson is shot after a fight, all the evidence points to his wife, who was found standing over his body holding the murder weapon. However, Murdoch believes her to be innocent, and sets out to find the real killer amid mounting racial tensions.
A skeptical Murdoch accompanies Arthur Conan Doyle to a seance. When the medium, Sarah Pensell, channels a murder victim and reveals the location of her body, Murdoch must come up with a rational explanation. Murdoch's skepticism is further shaken when Pensell reveals private information to him about his deceased fiancée, Liza.
A man is murdered in a church shortly before his wedding. When it is revealed that the marriage was a sham to claim an inheritance and that the victim was homosexual, Murdoch finds himself wrestling with his faith and the notion that homosexuality is a sin.
When a man is murdered shortly after engaging in a drunken brawl over the results of a ratting match, suspicion immediately falls upon the man he was fighting – Murdoch's estranged father.
The decomposing body of the Grand Theatre's former owner falls onto the stage during a performance of Macbeth. When exhumation of his supposed grave reveals yet another body, Murdoch suspects the troupe of actors know more than they are letting on.
When a member of the King's Rowing Club's Olympics team is murdered, suspicion quickly falls upon his predecessor, who was removed from the team when the victim joined. However, Murdoch suspects someone may be attempting to frame him, and must uncover the truth amid the other rowers' lies and misdirections.
Arthur Conan Doyle returns to Toronto to shadow Murdoch, hoping to find inspiration for a new detective novel. Murdoch reluctantly agrees and turns his attention to the brutal murder of a man whose ventriloquist son has confessed via his abusive dummy.
A well-liked philanthropist is murdered, and it appears that a group of Home Children from an institution which the victim supported may be to blame.
A hooded figure goes on a killing spree at a cutting edge brain research facility. As Murdoch investigates, he is contacted by medium Sarah Pensell, who tells him that she has foreseen the murderer's final victim – Murdoch himself.
Crabtree is assigned the difficult task of protecting Queen Victoria's playboy grandson, Prince Alfred, who is visiting Toronto. Meanwhile, Murdoch and Higgins investigate the murder of a woman who appears to be connected to the Irish Republican Brotherhood, who may be plotting to assassinate the Prince.
Murdoch must solve the baffling death of a man whose body is found hanging from a tree in the centre of a recently plowed field with no footprints in the surrounding soil. The discovery of nearby crop circles convinces Crabtree that Martian spaceships are to blame, but the discovery of a recent land ownership dispute involving the victim leads Murdoch to suspect more terrestrial suspects. The investigation brings Murdoch head-to-head with a ruthless Canadian Government agent, Terrence Meyers.