Murdoch and Ogden throw a housewarming party upon completion of their new avant-garde home, which was designed by Frank Lloyd Wright. The party is cut short when a man is cooked to the point of exploding in Murdoch's closet-sized microwave prototype. Despite officially retaining her position as city coroner, Julia has returned to medical school to study surgery, leaving Violet Hart to run the morgue day-to-day. Violet uses this to bolster her attempts to take over the morgue. Higgins quits the c
When one of Julia's patients dies after a seemingly successful surgery, she refuses to accept that it may have been her fault and becomes obsessed with the idea that it was murder. She enlists a reluctant Murdoch to investigate, and the two discover an unusual pattern of deaths among alcoholics in the ward. Crabtree has a brief courtship with a nursing student, Florence Nightingale Graham. He encourages her to sell a face cream she concocted; when it becomes a success, she elects to sell it unde
The eccentric Newsome family comes together for Higgins and Ruth's wedding, which quickly derails amidst disapproving relatives, jealous suitors, and a guest who keeps trying to murder Henry. Crabtree is blackmailed by the maid of honour, Effie Newsome, who forces him to help her steal a family heirloom. In the process, he attracts the unwanted attentions of a lustful bridesmaid.
The passing of Canada's 1906 immigration act leads to the mass deportation of criminal, unemployed, and sick migrants. Brackenreid bends the rules and helps a Greek carpenter avoid expulsion, a decision which blows up in his face when the man becomes the prime suspect in the murder of the Toronto immigration officer. A subsequent series of xenophobic articles by Louise Cherry incite violence against the local Greek community, leading Murdoch to suspect that Greek immigrants are being deliberatel
Canada is chosen as neutral ground for the signing of the Triple Entente treaty, but proves to be anything but when the French signatory is murdered. With the threat of German invasion looming in Europe, Terrence Meyers forces Murdoch to pose as the French delegate in a desperate attempt to sign the treaty and prevent a world war.
An alien species intent on wiping out the human race invades Toronto, and Crabtree becomes humanity's last hope for salvation.
When the sadistic criminal who tortured and murdered Detective Watts' adoptive brother is exonerated and released from prison, Watts kills him. Despite claiming self-defense, discrepancies in Watts' statement lead Murdoch to suspect that Watts took justice into his own hands and murdered the man in revenge for his brother's death. Crabtree hires Higgins as a trainee mechanic at his automobile repair shop.
Murdoch investigates the apparent double suicide of a wealthy couple who drowned in their swimming pool. Crabtree is sued over a faulty repair job by Higgins which has caused an accident, and butts heads with the plaintiff's attorney, Effie Newsome.
When Brackenreid travels to St. Marys at the behest of a former lover without informing his family or friends, John Brackenreid becomes increasingly concerned about his father's safety and sets out to find him.
An Italian detective implores Murdoch to investigate when treasures stolen from a Neapolitan museum are smuggled into Toronto. When one of the thieves is found dead, Crabtree goes undercover as a wealthy antiques collector in order to lure out the killer. Hoping to take the financial strain off Henry, Ruth gets a job as an apprentice nurse. Believing his marriage to be over, Brackenreid bids farewell to John and leaves home for good with Dan Seavey on the Wanderer.
Constables Crabtree and Brackenreid are tasked with transporting a convicted axe murderer to prison. When she escapes during transit and returns to her home town, supposedly seeking revenge on all those who helped to convict her, Detective Watts steps in to help recapture her. Murdoch and Ogden are disappointed when a police handbook outlining the latest investigative techniques fails to mention any of their scientific innovations. With the backing of a publisher, the two start writing their own
Murdoch's distressing childhood memories are evoked while investigating the death of an orphan under the care of the same Jesuit priest who taught him.
Inventor Nikola Tesla assists Murdoch in an investigation into the death of a man experimenting with invisibility.
Murdoch investigates an apparent arson death, and reveals a personal history in the process.
A man is electrocuted during a typing contest, but Murdoch suspects that he wasn't the intended target.
A series of murders occurs after Murdoch and Dr. Ogden's book is released.Excerpts written by Carol Hay, Paul Aitken, Alexandra Zarowny, Mary Pedersen and Dan TrottaExcerpts directed by Laurie Lynd, Cal Coons, Farhad Mann, Harvey Crossland and Alison Reid
Murdoch goes after a promotion during a raid on an opium den where a constable is shot.
Murdoch suspects John is being framed for murder by Inspector McWorthy and Brackenreid goes after the corrupt copper.