Red Chinese agent Wo Fat uses a sensory deprivation chamber to procure information from U.S. agents. Steve McGarrett, head of Hawaii Five-O, investigates the death of a close friend who appears to have drowned. Steve's knowledge about his friend and a mysterious white substance lead him into a high-level intelligence matter involving a foreign agent. McGarrett, head of Hawaii's state police force, poses as "control," possessor of the names of other agents. He allows himself to be captured and p
The governor of Hawaii assigns McGarrett to break a ring of con artists swindling/killing visiting rich widows. Kevin McCarthy, Louise Troy, Arlene McQuade, June Dayton and Patricia Smith guest stars. NOTE: First appearance of James MacArthur (as Danny "Danno" Williams), Richard Denning (as the governor), Maggi Parker (as McGarrett's secretary, May) and Peggy Ryan (as the governor's secretary, Mildred). Ryan would appear as McGarrett's new secretary, Jenny Sherman, from Seasons 2 to 8. Herman We
Victor Reese and his wife Nora are conning rich widows out of their savings, and then poisoning them and dumping them in the ocean. McGarrett and company hatch a plan to use a female officer to trap the duo.
A publicity stunt by a rock singer (Sal Mineo) to stage his own kidnapping backfires when ransom is offered. Harold J. Stone and Sam Melville (actor) guest stars.
A young singer, Bobby George, plans his own kidnapping as a stunt, but when his father offers $500,000 for his release, his co-conspirators decide to double-cross him and take the money.
The Five-O team works overtime when Danny is indicted for the murder of an apparently unarmed teenage boy. Gavin MacLeod, Luana Anders, Danny Kamekona and Charlotte Stewart guest star. NOTE #1: Edward Tom (uncredited) appears as Che Fong. NOTE #2: The evidence shows Danny fired his gun at a closed door lock with the armed suspect out of sight so Danny would have been acquitted as he was firing to break the door lock and was not firing with malice at the suspect. The sequel to this episode comes
The owner of a tuna boat uses his craft to smuggle gold bars into the islands. This episode contains the first use of McGarrett's three-word catchphrase, "Book 'em, Danno". Marj Dusay, Kaz Garas and Paul Richards guest star. NOTE: Richard Denning appears as Philip Grey, a U. S. Treasury agent.
McGarrett goes under cover in a California prison to find the connection between a girl's death and the theft of a gem collection. Don Knight guest stars.
After a girl dies during a high speed chase, a trail of clues leads McGarrett to a Los Angeles prison, where he must act the part of convict Steve Crowley to gain the trust of his cellmate for a break-out, which will help reveal the plans of the crime.
A U.S. serviceman, in Hawaii for R&R, becomes a pawn in a fight for control of a numbers syndicate. The head of the outfit is killed and the serviceman has been framed for it. Five-O races to solve the killing, shut down the numbers syndicate and prevent the serviceman from becoming the next homicide victim. Johnny Crawford, Anne Helm, Will Kuluva, Jonathan Goldsmith, Randall Duk Kim, Richard Benedict, Herman Wedemeyer guest star.
While searching for the killer who critically wounded Steve, Danny foolishly tips his hand to the killer (John Larch) when he questions the suspect's wife instead of staking out her home.
When McGarrett is shot and badly wounded on a beachside jog, Danno and the team must work feverishly to find the culprit and prevent him from committing any more murders.
McGarrett must protect a protect a mob underboss so he is able to testify against his superior, Joe Matsukino. However, Matsukino has many tricks up his sleeve to silence his former colleague permanently…
A Marine Vietnam veteran (Yaphet Kotto) suffers a breakdown and, believing he is back in Vietnam, takes Danny hostage in a hospital ward, and Steve is willing to risk the lives of everyone in the ward to save him.
McGarrett attempts to get the goods on David Stone (Ed Flanders), a professor-turned-guru who introduces young people to drugs, but does not use them himself.
A man carrying bubonic plague arrives in the islands the same time as plans for a top-secret weapon vanish. David Opatoshu, Nancy Kovack, Soon-Tek Oh, Herb Jeffries, Jackie Coogan, Victor Sen Yung guest star.
A man is found dead after having been robbed by a motorcyclist with a gun, and McGarrett is shocked to discover that the man was suffering from bubonic plague. The islands are quarantined, and the team must follow a series of clues to discover the cause of the outbreak.
Big Chicken returns in a tense prison hostage drama when McGarrett has to give himself over to the criminals as a bargaining chip and use psychology to take control of the situation.
A successful young boxer is murdered, and McGarrett has to find the murderer before the grieving father (a policeman himself) does. Jessie White, Peter Mark Richman, Jean Hale, Hal Baylor, Charles Lampkin and Frank de Kova guest star.
McGarrett travels to Los Angeles to help his sister (Nancy Malone) deal with her child's cancer and make the correct decision about a quack (Joanne Linville).
When the son of McGarrett's sister falls ill with cancer and she becomes involved in ‘naturology', her husband calls in Steve to investigate and persuade her to stop paying for the useless treatments. However, the quack doctor sets up a court case to prevent McGarrett from closing her practice.
A murder rocks a tight-knit group of left-wing hippies running Peace magazine. Law and order triumphs. Stewart Moss, Lee Paul, Ann Prentiss guest star.
McGarrett goes undercover as a safe-cracker to join a gang planning a robbery at sea, with a mastermind who delivers instructions by tape. Gerald S. O'Loughlin, Antoinette Bower, Than Wyenn, Eddie Dew guest star. NOTE: Going by production order, this is the back story of Carl Swanson portrayed by Gerald S. O'Loughlin which concludes in Episode 17 ("The Box").
Chin Ho and Dan Williams are tracking a safecracker but he pulls a gun and Danno ends up shooting him. McGarrett takes his identity of Harry Brown and must infiltrate a sophisticated gang of international thieves.
Sam Kalakua, a distant cousin of Kono, is being frightened into an early grave by an fake apparition of a Hawaiian god created by his nephew, who wants to sell the estate to a land merchant.