After officer Duke is implicated in the slaying of an underworld figure, McGarrett and the Five-O team must clear Duke and uncover the real killers. Michael Ansara and George Chakiris guest star. NOTE: The full name of Herman Wedemeyer's character Duke is revealed as Edward "Duke" Lukela (HPD badge number 270).
When two of an egomanical racing car driver's mechanics are murdered, suspicion falls on the driver's glamorous fiancee. Ricardo Montalbán and Diana Muldaur guest star. A stock shot of a exploding car wrecks is from 4/1 "Highest Castle, Deepest Grave"
A private investigator, Sam Tolliver, arrives from Texas to help an old friend who is being blackmailed and is at risk of being killed if he doesn't pay up, but he ends up wanting to become part of the blackmail operation.
Danno shoots an apparently armed teenager but finds that he was mistaken, and public opinion and the teen's brother turn against him. McGarrett must act to defuse the potentially explosive situation.
Wo Fat is suspected of being behind the theft of a secret ballistic missile device, and McGarrett uncovers a plot to get the device into the hands of the highest bidder. Wo Fat is arrested for espionage and murder by McGarrett, who in a last second twist ending receives a shocking secret from Jonathan Kaye (Joseph Sirola). Soon-Tek Oh appears as Tom Wong. Chin Ho Kelly's matenal uncle is head of the Wong tong. A shot of a hit and run accident would be repeated. NOTE: Final series appearance of J
An Army officer devises a bizarre scheme to kidnap a top government scientist and collect a ransom of one million dollars in diamonds. Bill Edwards as Jonathan Kaye. Clu Gulager and Michael Conrad guest star. NOTE: Bill Edwards takes over the role of Jonathan Kaye and would continue the role until Season 10.
A doctor tracking venereal disease is murdered, and Five-O must track the series of encounters to find out who is a carrier. Their investigation is made doubly important by the murder of a young woman who is close to a upcoming politician. He seems a likely suspect but McGarrett suspects a deeper plot.
Danno stumbles on a plot to assassinate a Chinese diplomat and suffers memory loss. McGarrett, Chin and Ben have to try to help him reconstruct the details. Philip Ahn and Keenan Wynn guest star in this episode.
The son (Robert Drivas) of the head of a family-dominated crime syndicate (Harold Gould) masterminds a series of small-time robberies. Eventually McGarrett catches him, but it doesn't end there... Luther Adler also guest stars as the Vashon patriarch.
With his son shot dead by McGarrett, Honore Vashon (Harold Gould) and his father Dominic (Luther Adler) are determined to see the Five-O chief pay the ultimate price.
With his grandson dead and his son in prison, Dominic (Luther Adler) sets in motion a scheme to frame McGarrett for the murder of a just-released drug pusher. NOTE: The sequel to this episode appears in Season 8, titled "The Case Against McGarrett".
McGarrett is assigned to preserve security and ensure an orderly trial after a series of bomb threats follows the arrest of a band of Hawaiian vigilantes.
In this comic relief episode, a husband-and-wife team of con artists accidentally make a bigger score than they ever imagined. The problem is not only have they've ripped off a mobster who wants his money back -- and will gladly kill to do so-but they find themselves stalked by another crime gang after the money as well!.Andy Griffith, Joyce Van Patten and Harold Sakata guest stars.
Five-O investigates after children are kidnapped and sold to an attorney operating a child-stealing racket on the Mainland. Richard Hatch, Meg Foster, Richard Anderson and Jack Hogan guest stars.
An underworld fringe character (Patty Duke) agrees to turn state's evidence against a mobster (Lane Bradford) if McGarrett releases her from prison and arranges her wedding to the father (Larry Kert) of her unborn child. McGarrett reconnects with a former lover (Carol Lawrence).
A psychotic electronics wizard (Greg Mullavey) threatens a psychiatrist (Robert Foxworth) and his patients through wiretapping.
Five-O has to solve the riddle of how a suspected killer (Monte Markham) can appear to be in two places at the same time.
A brilliant but unscruplious businessman (Richard Basehart) conceives a daring and seemingly foolproof scheme to rob the Honolulu Stock Exchange. Jack Hogan guest stars.
An obscure shopkeeper (Nehemiah Persoff) becomes the catalyst in a plot to assassinate a high-level Iron Curtain defector (Mark Lenard). Malachi Throne guest stars. NOTE: Bill Edwards as W.D. "Bill" Druthers.
Two ineffectual crooks (Jackie Coogan and Ron Feinberg) kidnap a little girl and hold her hostage on a hillside bunker. Tisha Sterling and Nina Foch guest stars. NOTE: Due to poor health, this was the final episode to be co-written by series creator Leonard Freeman. Same bunker location and footage used for "…And I Want Some Candy and a Gun That Shoots" (season 4, episode 6).
A travel agent operating gambling junkets is slain as a warning to his partners to stop competing for the gambling business. Milton Selzer and Carole Kai guest star. Kwan Hi Lim as Hank Yoshigo.
A gang member (Erik Estrada) under investigation by Five-O for extortion is courting the daughter (Irene Tsu) of Chin Ho, and they appear headed for a wedding.
A cat burglar strikes at the home of a socially prominent island family, setting off a series of fast-moving events that lead to his death. It soon develops that the dowager at the center of these events belongs to a noble, if not royal, family and has plans for reinstating the overthrown monarchy of the nation of her birth. Eric Braeden and Beulah Quo guest stars.
One of the jurors in a murder trial is being blackmailed to produce a hung jury, and Five-O has to find out the motive behind his consistent "not guilty" vote and prevent a mistrial.