The New Orleans team investigate the discovery of a severed leg found at a marina with the leg later revealed to have belonged to a recently murdered Navy Petty Officer Second Class who Pride mentored, prompting the team to investigate the crime. Brody, having joined the NCIS: New Orleans team on a permanent basis (in the NCIS season eleven episode, "Crescent City") is trying to get acquainted with New Orleans. NCIS Medical Examiner, Dr. Donald "Ducky" Mallard later offers both Wade and Pride so
When a Navy lieutenant on liberty dies in downtown New Orleans after being hit by a taxi, the team investigate what happened, but things soon take a turn when the autopsy reveals that the victim died of the bubonic plague and that the death is connected to a potential bioterrorist attack on a Navy ship, the U.S.S. Geronimo. As the team begin rounding up those assigned to the ship, they receive assistance from NCIS Director Leon Vance with CDC officer Carol Wilson and NCIS Special Agent Anthony "
When a bus crashes into a ditch resulting in three prisoners who were en route to the Naval Brig in Charleston escaping and the deaths of two security guards and a prisoner, the team soon discovers that one of them is a wanted criminal who poses a threat to national security. NCIS Director Leon Vance and Pride's friend, fellow NCIS Special Agent Leroy Jethro Gibbs both assist in the search with the investigation.
At a New Orleans Polytechnic University sorority house party, Tilda finds Natalie Lane with Navy SEAL PO1 T.J. Blake who was shot dead. University Police Officer Mike Banton responds first. Blake's BUDS instructor, Master Chief Erik T. Benson, directs Pride to Max Wolf; "not a SEAL" but a mercenary from their classified Somalia mission. LaSalle's college friend Heather confirms Blake and Wolf argued. Wolf claims Natalie is a hooker. LaSalle consults his C.I., Ross P, while Pride questions Tilda
When a chief warrant officer who specialized in counterintelligence is found dead from waterboarding, the team discover that the victim's wife has been kidnapped and is being held for ransom. FBI agent Tobias Fornell arrives in New Orleans to assist Pride and the team with the case.
As New Orleans prepares to celebrate Halloween, a Naval Staff Judge Advocate is found in a cemetery murdered "vampire-style" with the team discovering that an unlikely suspect is responsible and that a woman's life is hanging in the balance. Meanwhile, Brody and LaSalle compare costumes.
Navy Commander Darby Wilson, with top secret clearance at the Office of Naval Research, is killed by another motorist, and his assistant Rebecca Ortega is shot to death. The neighbor Bart Roberts says Darby and his wife Katherine always argued, and Rebecca visited regularly. Navy Captain Roger Marcus, concerned about sensitive intelligence, says Wilson was a tech liaison with Axelrod Industries. NCIS Special Agent Meredith Brody learns that Rebecca was involved with Lieutenant Clementine Hill, n
A petty officer is found dead in a Mardi Gras float storage facility with an engagement ring and proposal plan in hand. The investigation takes a mysterious turn when the team are unable to locate his supposed long-term girlfriend, but things change when it is revealed that a murderous Colombian assassin is in the city and plan on killing a group of Navy and Marine personnel who hope to stop the flow of drugs into South America.
The team investigates a 40-year-old cold case about a murder of a chief petty officer which hits close to home for Dr. Wade. However, an exhumation of the body reveals some unexpected evidence that may change everything. Meanwhile, Sebastian gets into the Thanksgiving mood and Laurel brings home her boyfriend.
A former SEAL who hunts military impostors is found dead at a museum, and the team's investigation leads them to find the jacket of a Marine who was presumed killed in Afghanistan. When the investigation reveals that the Marine may still be alive, both Pride and LaSalle travel to Afghanistan in an attempt to bring him home. Meanwhile, Brody wonders about LaSalle's issues with Christmas.
While attending the Navy-Marine Relief Gala, a deadly explosion happens, putting Laurel Pride's boyfriend in the hospital. The team learns that Pride was the intended target and the assassination attempt could be related to one of his old cases.
CGIS Agent Abigail Borin busts Julio on human smuggling, then finds two murdered grad students aboard the research vessel Acadiana; diver/oceanographer Mark Post and ecologists/biologist Cindy Rutberg, and a third crew-member missing, biologist Anna Huntley, daughter of Navy Admiral Adam Huntley. After analyzing paint transfer, the high-end boat thief Clive Roberts is apprehended, but he has an alibi for the murders. Video footage is found that shows Anna holding a Beretta during the attack. Bro
A Navy lieutenant commander and a friend of Pride seeks his help to solve his impending murder after he learns he has been poisoned with a lethal dose of radiation. CGIS agent Abigail Borin pairs up with the team again.
A fellow NCIS agent is shot dead while on security detail for a high-ranking Navy admiral. The team's investigation leads them to discover that the agent was the target due to a secret he knew about a sick child's biological father. Meanwhile, Brody's past is brought up by the security detail leader.
The stabbing death of a Mardi Gras partygoer leads the team to uncover a gang's plans for a major robbery at the height of the festival. Meanwhile, tensions rise between Pride and Laurel when he learns that she has been secretly visiting Pride's father in prison.
After three Iraq tours and a Purple Heart, single and raising foster brothers Danny and C.J. Malloy, Navy recruiter Petty Officer Maggie Barringer, is murdered by a hit-and-run driver. NCIS finds Maggie's emails to Community Foster Partnership, who are withholding money intended for the children. Fellow foster parents Joe and Jane Trahan confirm, CFP "social worker" Sumner St. Croix earns millions while under investigation for fraud. Confronted by Pride, Sumner leaps to his death. Jefferson Pari
After events in "Baitfish," Det. Rolland Clarke finds Dr. Freddy Barlow and Pam Shore shot dead in Charleston, SC. LaSalle and Brody worry about Pride's obsession with catching Paul Jenks, aka "Baitfish," a C.I. that Pride used to bring down the Broussard crime family. Patton finds the connection between Barlow and Batfish; a cloned phone belonging to Frank Broussard at Slidell Federal Penitentiary. Pride arranges a deal to dismiss Frank's drug and bombing charges to get Baitfish, then meets wit
After a Naval officer is found dead in a strip club, the team discovers that his death matches the MO of two unsolved murders, leading them to a mural with the names of unprosecuted killers. The list suggests that a vigilante may be at work. Meanwhile, Brody's ex-fiancé pays her a surprise visit.
In the morgue, Wade, Danny, and Sebastian are held hostage by a criminal who wants a secret that is inside a dead body, forcing Pride and the rest of the team into a desperate race against time to resolve the situation before an FBI team take charge.
A Navy commander's adopted baby daughter is kidnapped when he leaves her in the car while taking groceries inside, prompting the NCIS team to launch a search for the missing baby. CGIS agent Abigail Borin returns to help them with the case.
LaSalle and his girlfriend Savannah Kelly find Cade's girlfriend Windi Stewart dead in the trunk of Cade's car. Pride takes LaSalle off the case as NOPD Captain Det. Jim Messier investigates. Detectives Simms and Carlyle interrogate Cade. Pride and Brody question Windi's mother Susan about other boyfriends. Pride sends LaSalle to work with undercover ATF Agent Sonja Percy regarding Navy M16s and Beretta M9s stolen by Petty Officer Tom Lyons, but LaSalle insists on helping Cade. He and Brody find
In the aftermath of Savannah's murder and with the crime scene later being attacked resulting in the deaths of two officers and four more injured (as well as Brody who suffers a cut to her right arm), the team go into overdrive as all of New Orleans’ law enforcement searches for Baitfish. LaSalle seeks revenge for Savannah's death at Baitfish's hand. However, things get complicated when it is revealed Sasha and Baitfish have turned on each other and both are trying to get rid of the other.
Following a murder at the port in which a Navy officer dies after having his throat slit, Pride and the team investigate and discover that a dangerous West African terrorist has secretly infiltrated the city and is plotting an attack that could leave the entire population gravely ill with radiation poisoning.