The grand opening of Chicago Med's emergency department is interrupted by victims of an "L" subway train crash, pushing the staff to their limits. Dr. Will Halstead and the new trauma fellow Dr. Connor Rhodes butt heads when the latter pulls rank when it comes to treating patients. Pregnant pediatrician Dr. Natalie Manning reveals that her husband was killed during his tour of duty in Afghanistan when she meets Dr Rhodes on the spot she relaxes at. Medical student Sarah Reese's first days on rot
Dr. Manning treats a fourteen-year-old girl who gave birth and abandoned her baby son in an alley two blocks from the hospital. Dr Choi and Dr Rhodes lock heads because of Dr Choi's reckless decision of taking the umbilical cord out on his own since the OB-GYN was busy with a delivery. Dr. Charles and Reese treat a woman with a false case of dementia which is re-classified as hydrocephalus. Dr. Halstead treats a patient claiming he has suffered a heart attack which later turns much worse. Dr Man
Dr Halstead tries to apologize to Dr Manning for whatever he said the other day but the latter is quite angry at him. Dr. Choi asks for Dr. Charles' help in finding out why his army veteran patient seems to have diabetes even though he has none of the risk factors. It turns out the veteran's wife had poisoned her own husband to stop him from going back to duty. Dr. Halstead treats a musician who is suffering from vertigo and may require dangerous surgery. Dr. Rhodes tries to treat a patient he's
A mass movie theater shooting sends Chicago Med on edge. Dr. Halstead treats a patient who got trampled during the incident who later becomes brain-dead. Sharon refuses to approve a liver transplant that Dr. Rhodes needs for his patient. Dr. Manning and Dr. Charles treat a patient with an apparent eating disorder. The person who stopped the shooter is questioned when it turns out the shooter did not have a gun. Dr. Rhodes is involved with Dr. Zanetti and they sleep together.
Herrmann's condition takes a dramatic turn when Dr. Rhodes performs emergency surgery on him. Kelly Severide and Dr. Rhodes clash when it comes to Herrmann's treatment. Dr. Choi, Dr. Charles, and Detective Jay Halstead investigate a woman from a Firehouse 51 call who was admitted after a possible suicide attempt. The doctors discover she was receiving high doses of chemotherapy for cancer she never had. April's younger brother has his first day on rotation and finds himself in over his head. Thi
Dr. Rhodes treats two patients who were found stowed away on an airplane. Later, he meets with Sharon and Homeland Security, who are trying to get the undocumented immigrants deported. Reese asks for Dr. Charles' help telling a young patient that he has a terminal disease. Dr. Manning goes into labor, while Dr. Halstead meets Helen (Annie Potts), her controlling mother-in-law.
Dr. Halstead treats an ex-convict who was arrested for armed carjacking. Dr. Rhodes, Dr. Choi, and Reese treat a couple who were on a first date. Sharon receives news that a federal law will keep the hospital from performing an important bone marrow transplant. Dr. Manning and her mother-in-law care for her newborn child.
Dr. Halstead and Dr. Manning, who is back from maternity leave, treat a child with multiple medical issues whose father may have been unintentionally abusing her. Dr. Choi diagnoses an old friend with colon cancer. Reese and April treat a seemingly inebriated patient and Dr. Rhodes catches the attention of a high-profile surgeon preparing to operate on a Saudi Arabian prince.
Dr. Halstead makes a decision that could cost him his job when he resuscitates a patient with stage four cancer who has a DNR in place. The nurses at the hospital ask their patients to fill out patient satisfaction cards. Reese and April care for a homeless man. Dr. Choi's issues surface after he treats a patient with a bipolar disorder.
Dr. Choi and Reese deal with an overbearing father while treating his son following a hockey incident. Dr. Halstead deals with the fallout from his last patient and butts heads with Dr. Manning. Dr. Rhodes and Dr. Downey perform a lung transplant on a 9/11 hero suffering from pulmonary fibrosis.
Dr. Halstead is faced with the lawsuit brought by the woman he resuscitated against a DNR. Reese diagnoses a patient with a flesh-eating disease, and Dr. Choi and Dr. Rhodes treat a patient with a failing heart. Dr. Manning diagnoses a young girl with an infectious bacterium, but her parents do not want her vaccinated. Sharon celebrates her wedding anniversary.
Dr. Halstead continues to deal with the fallout from the lawsuit brought against him by his DNR patient. A police officer tries to stop a DUI driver from being taken to surgery, leading to Maggie being arrested, and Dr. Manning misdiagnoses a mother of child abuse. Meanwhile, Dr. Charles and Reese diagnose a patient with suicidal thoughts and place him on psychological hold.
Still dealing with the fallout of his DNR patient, Dr. Halstead tries to organize a baptism for Dr. Manning's son Owen. April befriends the father of a patient who was rushed in for swallowing magnets. Dr. Reese performs a procedure for which she is not qualified on a patient while awaiting the results of her residency match and Dr. Charles diagnoses a patient with a rare disorder when he tries to saw off his own arm.
As Dr. Choi deals with his PTSD, he treats a veteran with an unusual heart problem. Dr. Manning treats a child who she originally thought was being abused by his father, until Dr. Charles makes a shocking diagnosis to the patient's brother. Dr. Rhodes must deal with the fallout of a child dying on his operating table. April starts to date a young patient's father, against Maggie's advice. Reese faints in front of Dr. Halstead, and it turns out she does not want to leave the ER for pathology, whi
Dr. Choi deals with a surrogate mother who is at 32 weeks and needs an emergency c-section because the baby is in distress but tries to refuse, because she will not receive her bonus if it is not full-term. Meanwhile, Dr. Halstead treats a pair of brothers from his high school who used to bully him. Dr. Manning and Dr. Charles treat a patient with severe stomach pains. Also, April gets annoyed when she catches her brother running a side business without a license. Dr. Rhodes avoids seeing his si
Dr. Charles and Dr. Rhodes have a patient presenting with mental and heart problems, allegedly with Lewy Body dementia. It takes some thought, but they sort out the initial misdiagnosis. Meanwhile, Dr. Manning and Reese treat a dog biting victim, Dr. Choi tags along with the paramedics and receives a call from a burn victim who lives like a hoarder. Meanwhile, Sharon warns everyone at the hospital to be on their professional behavior when the Joint Commission visits.
Dr. Halstead and April butt heads when it comes to treating a patient with severe alcohol withdrawals and a broken leg. Meanwhile, Dr. Manning has a cardiac event when she loses her wedding ring, Dr. Rhodes is forced to perform bloodless surgery because of a patient who is a Jehovah's Witness and won't take a blood transfusion. Reese and Dr. Charles deals with elderly patients with the same symptoms.
Dr. Rhodes regrets to inform Dr. Downey that his liver cancer has spread to the brain and is not curable. Dr. Manning and Reese deal with an infant patient with multiple medical issues. Sharon learns that her husband is leaving her. Dr. Choi consults Dr. Charles about the parrot he rescued from the hoarder's house (in "Disorder") and gets a surprising suggestion. Also, Dr. Halstead bothers April to get an X-Ray following a serious fall she suffered. The X-Ray reveals April has tuberculosis. Rees