Maggie has resigned so Doris steps up as ED Charge Nurse. Frost treats a family of burn victims and discovers a fatality thought to be the wife was actually the husband's mistress. Ripley learns Asher is expecting and Archer is the father. Naomi Howard returns as a general surgery resident. Young ravers pulled from a collapsed building are cared for by the Gaffney staff: Charles counsels a boy with survivor's guilt while Lenox powers through an operation to separate fused sisters. Archer wraps h
As the ED staff dishes on the "Dasher" news, a visiting Will Halstead rushes in carrying Jasper, a downed teenage drug mule. Hostility between Ripley and Archer surfaces as they operate on a man whose artificial height extensions have become infected. Goodwin gives Halstead's young stepson, Owen, a notebook to journal about his upcoming brotherhood (his mother, Natalie Manning, and Will are expecting a baby). Asher discovers a soon-to-be father has gastric cancer. Lenox fearlessly stands up to a
Manning is determined to donate a kidney to Owen despite the risk to her unborn child and discouragement from Halstead, Archer, and Asher. Charles jars back the memory of a naval lieutenant in a dissociative fugue state who was found in the Chicago River. Goodwin, Lenox, and Frost mediate when a brain dead man's estranged parents request to extract his sperm over his lover's objections. Archer and Asher succeed in the kidney transfer, sparing Manning's baby. Halstead learns how much Owen loves h
Charles challenges automated FMRI diagnosis pushed by new psychiatrist Rabari when dealing with a furniture maker who deliberately severed his own hand. Frost bonds with a 10-year-old auto immune deficiency patient whose need for stem cells reveals an IVF mix-up in her biological parentage. Lenox tries to curb her reckless streak treating a violently abused newlywed. Ripley insists debt-ridden Frost become his roommate.
Halloween haunts the ED. Asher and Archer argue over how to co-parent. Charles deals with turning 65 while helping a foster child who suffers from "demon-face" syndrome. Goodwin is shocked by a volatile outburst from her ex-husband, Bert, as his dementia worsens. Det. Kim Burgess is called in to investigate the whereabouts of a coed's newborn. Ripley trick-or-treats with Sadie and her daughter, assuring he's committed to them. Lenox marvels at her irresponsible brother's turnabout as her own per
Goodwin's offspring (including long absent David) gather for a complicated good-bye to their dying father. Asher gives romantic advice to Sadie on Ripley and Howard on Frost. Lenox connects with Jabo, a tattoo artist, as she traces his anemia to blood-poisoning. The search for the pet rabbit of a hornet-stung patient brings flirtatious sparks between Frost and paramedic Novak (from Firehouse 51). Sadie breaks up with Ripley.
A rainstorm knocks out power at Gaffney amid usual turmoil. Ripley stalls the discharge of Devin Carter, a suspected abuser, so Lenox can check on the welfare of his wife. A terminal patient undergoes surgery to attend his child's birth. Archer's son, Sean, supports him being a father again. Charles and Rabari come down on opposite sides of continuing a drug trial on a gymnast. Frost's mojo creates a romantic triangle with Novak and Howard. Lenox is attacked by Carter in his house.
The day after the blackout, ED staffers face consequences for their actions. Lenox and Ripley cover for battered spouse, Faye, after she killed her husband who was holding them hostage. Goodwin reviews Archer and oncologist Kingston resuming a questionable surgery when the hospital's power went down. Charles considers retirement following his tough call denying a suicidal patient a heart transplant. Asher and Archer learn they are expecting a girl.
Road rage lands three patients in the ED: Asher delivers the baby of a cab passenger, Ripley hunts for the driver's Filipino family to approve surgery, and Charles and Rabari evaluate the agitator with a misdiagnosed hormone deficiency. Frost's "Nick of Time" costar, Ian, asks he consider appearing in the series reboot. Archer does not hit it off with Asher's conservative contractor dad. Charles' panic attacks increase. Goodwin strives to recall positive times with her late ex, Bert, before his
Frost clears paramedic Novak of overdosing a college basketball star when he proves the girl has an ultra rapid metabolism. Asher and Lenox discover an endangered second fetus in a surrogate. Ripley faces resistance from the grown abused daughter of a seemingly sweet dementia patient. Asher encourages Archer to date Kingston. Goodwin chooses a nursing home caregiver for a hospital externship over a board member's nephew. Mutual PTSD pushes Lenox and Ripley to hook up in a supply closet.
Charles' longtime friends, Drs. Howie and Suzie Mankiewicz, have a devastating decision when she faces high-risk brain surgery or permanent disability. Archer locks horns with a rodeo rider who refuses treatment for spinal injuries. A year after Sully's death, his widow Lynne and Ripley spread his ashes at Wrigley Field. Kingston interferes with Asher's diagnosis of a pregnant ex-cancer patient. Suzie does not survive in the OR. Lenox and Ripley are inspired to take their relationship beyond the
A trio of eager psych students shadow Charles on an intense day in the ED. Frost rejects his greedy, estranged parents when he and Asher treat an anemic teen whose mother sacrifices all to move them out of Chicago's cold. A patient who co-owns a pizza joint with his brother is diagnosed with celiac disease following a violent mental break. Goodwin performs an open heart procedure on a disgruntled board member during a chartered flight. One of Charles' charges switches majors after witnessing Len
Gaffney's ED converts into an isolated ward as the staff masks up to treat victims of a contagious toxin. Archer is furious when Asher risks exposure to perform a c-section in an ambulance outside the secured perimeter. Fire Squad members Cruz and Capp are infected and admitted. Frost tends to his recent ex, Novak. Charles breaks the news of a young firefighter's death to her mother. FBI agent Hailey Upton and army black op Jay Halstead (both former Chicago P.D.) team with Goodwin, Sgt. Voight,
Drunken St. Patrick's Day revelers descend on the ED. Charles makes Frost see his distrust of a re-diagnosed bipolar patient stems from unresolved anger he holds for his parents. Archer and Lenox treat injured buddies when a bucket list stunt goes wrong. Asher traces a divorcing woman's surprise pregnancy to an Ambien-induced tryst with her ex. Ripley is speechless when Lenox openly acknowledges their affair to Goodwin.
Expecting parents Esme and Jeremy Lockhart return to Gaffney: she in labor, he about to succumb to cancer. Charles' CBD patient, a lottery winner who relies on a Magic 8 Ball, offers to fund Rabari's research if it will cure her. Frost's father, James, has been lying about having MS when his actual ailment is a spinal tumor. Asher delivers the Lockharts' daughter while Archer helps Jeremy record messages to be played after his death. Frost reluctantly agrees to act in the "Nick of Time" reboot,
A fateful 24 hours for Charles begins with a disconnected caller on a suicide hotline. This leads to daily rounds at the ED involving hostile denial from Ripley's sexually assaulted patient, a vindictive hypochondriac treated by Lenox, and a young boy in Frost's care who behaves like a cat. Confrontations continue: arguments with his daughter, Anna, and Goodwin; a dead end from Officer Atwater tracking the lost call; hallucinations of his late mother. Charles ends the day suffering a stroke, col
Neurosurgeon Abrams and Archer operate on Charles while he experiences guilty flashbacks of ex-wives, delinquent Ripley, Suzie Mankiewicz, and his difficult mother, leading to the discovery of his father's suicide as a teen. Asher objects to OBGYN Vera Lovell, Lenox's hipster replacement for her when she goes on maternity leave. Ripley and Frost both see Charles as an inspiring dad. The ED staff gathers in the waiting room. Memories confronted, Charles pulls through, waking with Goodwin at his h
A lack of surgeons and space forces Archer, Asher, and Ripley to operate on a family of car crash victims in the ER. Rabari resents Charles' early return after rehab, particularly when a concussed football player is re-assessed with PTSD. Goodwin connects her son, David, with his embittered biological father, Spencer. Lenox pushes a grieving parent to approve risky surgery on his boy. Frost treats Howard's studly boyfriend only to end up in her arms at the shift's end. Ripley cools things with i
Asher meets with her dad following a patient's difficult delivery and discovers her resemblance to her late mother (who died at her birth) has kept him distant. Frost quits the "Nick of Time" revival when told his co-star is Ainsley, the actress who seduced him as a teen, and that his avid father, James, knew about the affair. Ripley befriends Kip, Lenox's flighty brother, and learns of their family's tragic history with prion disease. Goodwin and Howard return expensive gifts from a board membe
Gaffney is thrown into chaos when a prison riot overwhelms the E.D. Goodwin and Charles prepare for a high-stakes board meeting.
Hannah faces one of the most challenging deliveries of her career. Frost navigates demanding times.