Shaun, Park, and Lim discover that a tonsillectomy patient's brother, a boy named Jordan, has cervical cancer in his throat, which he got in utero from his mother Sarah. While Jordan's treatment can wait, Sarah needs an immediate radical hysterectomy. She refuses, as she doesn't have anyone to rely on, until Park convinces her to make amends with her estranged brother Nick. Lea plans and throws an engagement party. At the party, Glassman gives a drunken toast, admitting that his wife has left hi
Salen and her company, Ethicure, take over the hospital; Glassman considers resigning, but soon accepts a deal to continue working. Andrews, Jordan, and Mateo treat Madeline, a young woman with terminal cancer. At Shaun's suggestion, Mateo performs an experimental T-cell treatment. Andrews is removed from the case for arguing in front of Salen. Madeline struggles with the sudden return of her birth mother. The two reconcile with Mateo's encouragement, but Salen chastises Lim and Mateo for priori
Andrews, Park, and Mateo treat a patient who has a chip placed in her head as part of an operation conducted by another doctor, but the company responsible wants to remove it from her. Shaun, Wolke, Jordan, and Lim treat a man who has severely damaged his face after crashing his bike. Both teams experience challenges to convince Salen that their approaches are worth taking however, despite some failure, Andrews settles on Mateo's solution and convinces Salen. Lea discovers that Shaun planned to
Shaun, Andrews, and Mateo treat Holly, a young girl whose father, Walt, has diagnosed her with visceral myopathy; after Walt is proven right, Salen orders the team to treat him like a consulting physician, causing Shaun to become dismissive and rude to the point that Andrews removes Shaun from the case. Although the team nearly has to remove most of Holly's intestines, Shaun prevents this by having them insert a feeding tube into her colon to relieve the pressure. Morgan and Park treat Gina, who
Shaun, Jordan, and Park treat Mr. Song, the victim of a hate crime who is diagnosed with a brain tumor; he refuses the surgery to remove it. After Song's condition worsens, Shaun convinces his daughter to approve the surgery; most of the tumor is removed and Song is left with permanent weakness on his left side, but he respects his daughter's decision. Lim and Asher treat Rosa, an ex-girlfriend of Mateo who was in Guatemala on a medical mission; Andrews later transfers Rosa to the county hospita
Shaun, Asher, and Lim treat Brandon, a man with internal injuries from a fall. At the same time, Park treats Ollie, a young boy who needs a heart transplant in order to survive, for which Brandon is a match; as a result, Park and Shaun clash over their desires to save their respective patients. After accepting that Brandon can't be saved, Shaun figures out a way to save his heart using embroidery and Ollie is saved, along with 63 other people who also received organs. Morgan treats Nira, who has
Glassman receives a surprise visit from his ex-wife, Ilana Reeves, who wants him to have a look at her new husband, Sunil, who has Lewy Body dementia and signs of a tumor; he is hesitant, but decides to try. Ilana forgives him for their daughter’s death and advises him to stay in San Jose for Shaun. Glassman decides to operate on Sunil and removes his tumor successfully. After looking at a church for a wedding venue, Shaun and Lea stumble upon a multiple-vehicle accident. At St. Bonaventure, Sha
Salen has the pharmacist fired and has him sign a non-disclosure agreement. Lim decides to build a case against her, discovering that the hospital has not in effect been taken over completely by Salen yet. Salen later threatens her by saying she will remember her betrayal to go behind her back. Andrews, Asher, and Jordan treat a young woman who previously had surgery and is in pain. They manage to remove clots in her body that started to spread to her heart and other vital organs. Lim, Shaun, an
After her fight with Shaun, Lea crashes with Jordan, who implores Shaun to let go of his doubts about Lea. Lim is demoted from her role as chief of surgery and the position is given to Andrews. She receives a job offer from another hospital, but declines. Instead, she enlists the other doctors to help her take down Salen; Park and Glassman agree to partake while Shaun, Jordan, and Morgan refuse. The team treats Nelly Dunn, a pop singer who can only speak using her electrolarynx. Although Shaun w
Glassman and Lea encourage Shaun to continue working to protect his reputation, which he does, vowing to focus on the medicine. Returning to work, Shaun assists Park with a man who has hurt his head, but they later discover he suffers from cancer due to a liver donated by his friend. Salen hinders Lim and her supporters' scheme by having her and Glassman immediately fired and Asher's and Park's residencies terminated. Andrews assures Lim he is standing up with them against Salen. Asher and Jorda
Andrews reinstates Lim as the Chief of Surgery, but has to shut down the clinic due to Morgan's revelation to Nira. Morgan works on becoming a better person, managing to save the clinic before returning it to Glassman, as she isn't ready for the responsibility yet. The Liu family's serious car accident brings them to the hospital, forcing Lim, Andrews, and Glassman to work together to save the parents. However, they struggle due to their anger at each other over how they handled Salen; they even
Shaun attempts to devise a plan to have sex with Lea after a nine-day hiatus and dry spell, seeking advice from his colleagues and Glassman. Lim, Park, and Asher treat Mariel Torres, who collapsed at the airport, and they discover a fungus in her lungs. During surgery, it bursts and starts leaking into her blood system, postponing a secondary surgery on her kidneys. Torres reveals to her boyfriend that she is an undocumented immigrant and he distances himself before later forgiving her and retur
Asher and Shaun treat 17-year-old Trent who has an infection in one of his fingers due to one of his many biohacking implants. Their efforts to treat his growing pain are hindered by Trent's troubling relationship with his mother as a result of his father leaving them. Although she is skeptical of his interests, Trent's mother eventually allows him to undergo an experimental operation proposed by Shaun in order for Trent to keep his hand. When Lea approaches Jordan for help regarding a sensor pr
After a potluck at the hospital, most of the staff begins acting strangely, leaving Glassman, Shaun, Morgan, and Jordan in charge; Morgan, Lea, and Asher eventually realize that Asher and Jerome accidentally used magic mushrooms in their sweet potatoes. During this time, Asher becomes insecure when Jerome doesn't want him to meet his college friends, Park is worried that he and Morgan are too opposite to work, Lim hallucinates snakes, and Andrews thinks that he's Spider-Man. Shaun and Glassman's
Lim and Shaun attend to an elderly woman in an iron lung, Joan, who is scheduled to have lung surgery when the iron lung suddenly fails. Lea goes out with Joan's roommate Sophie to find spare parts to fix the iron lung, going through quite the effort trying to get an engine from a 1938 Chevrolet. Despite the lung now being fixed, Joan is suffering from a rupture in one of her inner lungs. After one operation, she's reluctant to go through with the surgery. Sophie manages to convince her otherwis
As a film crew follows Shaun and Lea around, Shaun and Park are given their own surgical cases to test whether or not they are prepared to become attendings. A fire leaves Shaun treating Dana Bradley for facial burns and Park treating Grant Ferlin, a firefighter, for a fractured spine; Shaun makes a mistake during Dana’s debridement, worsening her condition, while Grant refuses a spinal fusion, wishing to preserve his career. Park enlists Lim's help to perform an alternative surgery, but Grant’s
Sophie's documentary changes focus onto Lea and her wedding plans. Claire temporarily returns to the hospital to assist with a tumor surgery on a young boy, Lucho, whom she brought from Guatemala for better care. Andrews and Lim sort the doctors into teams to remove the tumors in Lucho's brain, heart, and kidneys. Following the first surgery, Shaun concludes that they should have operated on Lucho's brain first, admitting that Lucho could die. While passing a strip club, Shaun realises that they
Park and Morgan treat Steph, a young woman paralyzed by a stroke. A lung operation results in Steph losing the limited amount of control that she had over her right hand. Morgan suggests they create a device attached to Steph's brain to allow her to communicate. Lea programs it using Steph’s voice; the surgery is successful. Asher's estranged father Yosel comes to the hospital, seeking his son's help to treat his terminal lung cancer. Shaun comes up with a treatment that could give Yosel up to a