Lim manages to call Andrews, who locks down the hospital. Shaun, Andrews, Glassman, and Jordan operate on Lim and Villanueva with the help of Jerome and Lea but argue over the best course of treatment to the point that Shaun defies Glassman's plan. Owen takes Asher, Morgan, and a patient, Ezra, hostage, complicated when Ezra needs emergency bowel surgery. Morgan convinces Owen to release her and Ezra. A remorseful Owen hands Asher his bullets before attempting to commit suicide by cop, resulting
On their first day as surgical attendings, Shaun and Park have to deal with a heart transplant and a neck tumor, respectively. Shaun's decision to perform a xenotransplant puts him at odds with new resident Dr. Danica "Danni" Powell, nearly leading him to fire her before changing his mind, while Park's patient Jeremiah is a shut-in who Jordan and Dr. Daniel "Danny" Perez try to help socialize more. When a pig, Wilbur, is brought in for the transplant, the staff struggles to go through with it be
Shaun, Asher, and Danny treat Julianne, a marriage counselor with a brain tumor; during the surgery to remove it, Julianne has what she believes to be a near-death experience, which Shaun believes to be a symptom of another tumor. Although Julianne considers dying to be with her husband, Danny convinces her to undergo surgery. However, she dies on the operating table with an autopsy confirming the second tumor. Park, Jordan, and Danni treat Katie, a girl with bipolar disorder whose parents disag
Shaun, Asher, and Danni treat Charlie, who got shrapnel in his arm during a military reenactment. Damage caused during surgery makes it appear as if his arm must be amputated, but Shaun finds a solution. Asher asks about Danni's military career, at first unintentionally offending her; after they make up, Danni opens up to him about it. Park, Jordan, and Danny treat Andy, a young man whose foot was severed while skinny dipping. Park works to keep the leg viable while the police search for Andy's
Shaun, Asher, and Danni treat Skylar, a musically talented young girl with liver failure from a genetic disorder; Skylar's illness reveals that she is the product of an affair between her mother and her father's former roommate Mick who is the only compatible donor for Skylar. Mick refuses, but reconsiders once Lea shows him a video of his daughter performing. Park, Jordan, and Danny treat Chris, a man with pancreatic cancer who is the caretaker of his brother Ollie who has a traumatic brain inj
During a heatwave, Shaun and Danni work on a case together, but Shaun struggles to work with her after finding out she advised Lim not to do the surgery that he proposed. Danni keeps contradicting him during their work and he shoots down her ideas. After their recent arguing, Shaun removes her from the case but, after his patient wants Danni back on and Glassman advises him to find common ground with her, he and Danni resolve their issues and they save the patient. The rest of the staff treat el
Andrews' ex-wife Isabel brings in Gena Cooper who gives birth to sextuplets; Andrews assigns a team of doctors to each of the babies. Lim's date Clay helps her find a solution to her and Danni's patient. Glassman and Jordan clash over their case before coming together to find a solution. Morgan and Park successfully treat two of the babies together, while Shaun faces memories of Lea's miscarriage while treating one of the babies with Danny. Ultimately, all six babies survive despite their variou
Morgan, Park, and Jordan treat Toni, a victim of sexual assault who resists the idea of getting a rape kit done. After pressuring Toni, Morgan eventually reveals that she is a rape survivor herself; opening up about her own trauma and regrets gets Toni to agree. Shaun, Asher, and Glassman treat Naveen, a woman who has an infection due to a retained surgical towel. Naveen's wife has to make the difficult choice of consenting to a full hysterectomy despite fears that her wife will never forgive he
Shaun implements a new rating system, putting Danny and Danni into a competition with each other as they treat Teddy, a young man with bulimia; Teddy's struggles remind Danny of his own problems and he helps Teddy reconcile with his brother. Park, Morgan, Jordan, and Asher treat Park's new girlfriend Lilly who has a sinus infection that has spread to her brain, leading to renewed clashing between Park and Morgan before they come up with a solution together. Morgan admits that she's worried they
Three months later Lim can walk with a cane, Lea's pregnancy is progressing, Danny returns to work under conditions, and Morgan prepares for her embryo implantation while trying to maintain a professional relationship with Park. Shaun enlists Glassman and Lim to fix a pregnancy complication, but isolates Lea in his attempts to protect her until Asher calls him out on it. Morgan, Park, Danny, and Jordan treat Drew, a young Gardner's syndrome patient who needs a small bowel transplant as well as a
While on their babymoon, Shaun and Lea witness a dog get hit by a car and Lea becomes emotionally involved, demanding that Shaun find a surgery to fix the dog's injuries. With Glassman's help, Shaun is able to save him. The two decide to adopt the dog before his family arrives to pick him up, having seen Lea's flyers. Lea admits to Glassman her fears about being a mother and Glassman opens up to Lea about Maddie and reassures her. Andrews, Park, Jordan, and Morgan treat Lalo, an immigrant with t
Lim, Asher, and Danny treat Bob, a long-term patient of Lim's who is in heart failure. Asher disagrees with Lim's proposed surgery, believing it too risky, and Danny refuses to back him up despite his own doubts. Ultimately, Asher proves to be right, but he and Lim are able to find a solution together that will buy Bob time to find a suitable donor heart. Shaun and Jordan treat Kelly, a 13-year-old girl who has a tumor as a result of having had sex. Shaun and Jordan clash over whether or not to
Shaun, Asher, and Danny treat Ricky, a boy with naegleria fowleri whose parents' marriage is being torn apart by their inability to agree on how to raise him. When Ricky's condition worsens, they are forced to remove a small piece of his brain to save Ricky's life, although he doesn't appear to suffer any negative side effects from it. Park helps Morgan with her first clinical trial patients, only for one, Mr. Riggs, to have a preexisting condition, causing Morgan to believe that he either lied
Shaun, Park, and Danny treat Nathan, a young boy with moyamoya disease whose predicament hits Park hard as a parent while Shaun has trouble connecting with him as more than a patient. Rather than put Nathan through multiple brain surgeries, Park and Shaun find a single solution and Shaun displays empathy for Nathan by wrapping his toy dog's head in bandages to make him feel better. Jordan, Lim, and Asher treat Evelyn Allen, Jordan's grandmother, leading to Jordan clashing with Lim over the best
Sonja is a pregnant woman whose condition puts both her and her baby Esther's lives in jeopardy. Morgan and Jordan disagree as to whether halting the pregnancy is the best option, whereas Sonja is ready to risk her life for a slim chance at saving her baby. Jordan finally convinces Sonja to opt for an abortion by telling her about her own, but she first arranges for Esther to be baptized. Park hesitantly treats Joe, the man who tarnished his marriage and who now seeks Park's forgiveness. Park sa
Shaun is sued by Bob Patton, a man whose hand he amputated after Shaun and Park found Bob and his sister in the aftermath of a car crash. Bob contends the amputation was unnecessary; Park expresses his own reservations. Glassman refers Shaun to his lawyer friend Janet Stewart for aid, but Shaun chooses Joni DeGroot, a lawyer in Janet's firm who has OCD, complicating Joni's ability to practice law. Despite Janet and Glassman's advice to settle, Shaun decides to go to trial. Despite a rocky start,
Carter, a boy with an inverted heart, is treated by Park, Asher, and Lim as his mother Bianca struggles to make amends for deserting him years ago. Despite complications, the three are able to repair Carter's heart and Bianca reconciles with her own mother. Shaun, Jared, and Jordan care for Yara, a young girl suffering from uncontrollable laughter caused by a benign brain tumor. Jared's zeal to prove himself causes him to take shortcuts, placing him at odds with Shaun, who struggles to balance b
Shaun investigates why Glassman missed two sutures from the previous episode's surgery and discovers signs that his brain cancer has returned. He asks Glassman to have another MRI, which he initially refuses, but eventually accepts after Shaun admits he is scared of losing him just as he is becoming a father. Jared and Jordan treat Daphne Garcia, who is diagnosed with sleep apnea after a physical scan. Daphne becomes septic while undergoing dialysis. Jordan convinces her to have a surgery which
Brady is a patient who was nearly cut in half by a piece of metal. Andrews argues for amputation of his lower half while Lim wants to save it, causing the two doctors to clash, straining their relationship, especially when Andrews still distrusts Jared over their previous conflict. While trying to find a solution, Jared and Danny clash over Jared's overly cautious attitude. Jared later admits to Asher that his attempts at an experimental surgery to save a cancer patient resulted in the patient's
Andrews, Jordan, and Asher treat Eddie Richter, a carpenter friend of Andrews who has wart-like growths over his body. His affiliation with religion makes Asher skeptical and rant in front of Jerome, who later distances himself from him, noting that Asher didn't respect his opinion and views. Andrews decides to go ahead with a risky surgery for Eddie, which he survives at first, but he then dies from a blood clot afterwards. Asher manages to reel Jerome back in and apologizes in front of his fri
Lim moves to take Glassman off surgeries, but he resists and threatens to sue. Lim manages to reach a compromise with Andrews. Shaun, Jordan, and Danny treat a man who suffered a head injury in a car accident. They discover that he has a tumor in his brain, but he initially declines the surgery due to his personality shift towards his daughter. Shaun reluctantly asks Glassman to help convince the man to have the surgery. Shaun's constant oversight of Glassman forces him to remove him from the ca
While transporting a patient to the hospital, Danny, Jared, and Jerome are involved in a multi-vehicle crash that leaves Danny seriously injured. Due to his addiction, Danny refuses pain medication, but Jordan is forced to give it to him when Danny's pain threatens his life. Although Danny ultimately forgives Jordan, he decides to move back to Texas to recover with his family's help and support to avoid relapsing, but he first goes on a makeshift date with Jordan. Asher pulls Shaun in to help wi